AAH53550.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,035 Da
NCBI Official Full Name
Peroxiredoxin 6
NCBI Official Synonym Full Names
peroxiredoxin 6
NCBI Official Synonym Symbols
PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m [Similar Products]
NCBI Protein Information
peroxiredoxin-6
UniProt Protein Name
Peroxiredoxin-6
UniProt Synonym Protein Names
1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2 (EC:3.1.1.4
UniProt Synonym Gene Names
NCBI Summary for PRDX6
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
UniProt Comments for PRDX6
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl grup of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis.
Research Articles on PRDX6
Precautions
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Disclaimer
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Products associated with PRDX6 antibody pair kit
Pathways associated with PRDX6 antibody pair kit
Diseases associated with PRDX6 antibody pair kit
Organs/Tissues associated with PRDX6 antibody pair kit
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