NP_112462.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
169,743 Da
NCBI Official Full Name
A-kinase anchor protein 12
NCBI Official Synonym Full Names
A kinase (PRKA) anchor protein (gravin) 12
NCBI Official Synonym Symbols
Srcs5; SSeCKS; Tsga12; AI317366 [Similar Products]
NCBI Protein Information
A-kinase anchor protein 12
UniProt Protein Name
A-kinase anchor protein 12
UniProt Synonym Protein Names
Germ cell lineage protein gercelin; Src-suppressed C kinase substrate; SSeCKS
UniProt Synonym Gene Names
UniProt Entry Name
AKA12_MOUSE
UniProt Comments for Akap12
AKAP12: a scaffold protein that contains 3 conserved PKA binding motifs. Suppresses podosome formation, inhibits RhoA and Cdc42 activity, and inhibits v-Src-induced oncogenic growth in NIH3T3. May inhibit Src-induced oncogenesis by reestablishing actin-based non-invasive cytoskeletal architecture.
Protein type: Adaptor/scaffold
Cellular Component: cytoplasm; cytoskeleton; focal adhesion; membrane; plasma membrane
Molecular Function: adenylate cyclase binding; protein kinase A binding; receptor signaling complex scaffold activity
Biological Process: positive regulation of cAMP biosynthetic process; protein targeting; signal transduction
Research Articles on Akap12
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Products associated with anti-Akap12 antibody
Pathways associated with anti-Akap12 antibody
Diseases associated with anti-Akap12 antibody
Organs/Tissues associated with anti-Akap12 antibody
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