BAC24016.1
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
guanylyl cyclase alpha 1 subunit
NCBI Official Synonym Full Names
guanylate cyclase 1, soluble, alpha 3
NCBI Official Synonym Symbols
NCBI Protein Information
guanylate cyclase soluble subunit alpha-3
UniProt Protein Name
Guanylyl cyclase alpha 1 subunit
UniProt Synonym Protein Names
Guanylyl cyclase alpha 1 subunit
UniProt Entry Name
Q8CJD2_RAT
NCBI Summary for Gucy1a3
soluble guanylate cyclase subunit that forms a heterodimer with Gucy1b3; may also function as an intracellular nitric oxide receptor [RGD, Feb 2006]
UniProt Comments for Gucy1a3
GUCY1A3: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Protein type: Lyase; EC 4.6.1.2; Nucleotide Metabolism - purine; Receptor, misc.; Guanylyl cyclase
Cellular Component: cytosol; guanylate cyclase complex, soluble; plasma membrane; protein complex
Molecular Function: adenylate cyclase activity; cytidylate cyclase activity; GTP binding; guanylate cyclase activity; heme binding; ion binding; nucleotide binding; protein heterodimerization activity
Biological Process: cAMP biosynthetic process; cGMP biosynthetic process; nitric oxide mediated signal transduction; positive regulation of cGMP biosynthetic process; regulation of blood pressure; relaxation of vascular smooth muscle; response to defense-related host nitric oxide production; response to herbicide; response to organic cyclic substance
Research Articles on Gucy1a3
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Pathways associated with anti-Gucy1a3 antibody
Organs/Tissues associated with anti-Gucy1a3 antibody
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