NP_057691.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
armadillo repeat-containing X-linked protein 3
NCBI Official Synonym Full Names
armadillo repeat containing, X-linked 3
NCBI Protein Information
armadillo repeat-containing X-linked protein 3
UniProt Protein Name
Armadillo repeat-containing X-linked protein 3
UniProt Synonym Protein Names
ARM protein lost in epithelial cancers on chromosome X 3; Protein ALEX3
UniProt Synonym Gene Names
UniProt Entry Name
ARMX3_HUMAN
NCBI Summary for ARMCX3
This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ARMCX3
ARMCX3: an armadillo-repeat protein. Armadillo proteins function in multiple processes including intracellular signalling, cytoskeletal regulation, and transcriptional regulation. Armadillo proteins include beta-catenin, the junctional plaque protein plakoglobin, the adenomatous polyposis coli (APC) tumour suppressor protein, and the nuclear transport factor importin-alpha.
Protein type: Mitochondrial; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xq22.1
Cellular Component: integral to mitochondrial outer membrane
Biological Process: positive regulation of transcription from RNA polymerase II promoter
Product References and Citations for anti-ARMCX3 antibody
Mou, Z., et al. J. Biol. Chem. 284(20):13629-13640(2009) Olsen, J.V., et al. Cell 127(3):635-648(2006) Olsen, J.V., et al. Cell 127(3):635-648(2006) Ross, M.T., et al. Nature 434(7031):325-337(2005) Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Research Articles on ARMCX3
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Organs/Tissues associated with anti-ARMCX3 antibody
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