Q9UKP5.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,189 Da
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 6
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif 6
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 6
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 6
UniProt Synonym Gene Names
UniProt Entry Name
ATS6_HUMAN
NCBI Summary for ADAMTS6
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016]
UniProt Comments for ADAMTS6
ADAMTS6: a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]
Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide; EC 3.4.24.-; Protease
Chromosomal Location of Human Ortholog: 5q12
Molecular Function: metallopeptidase activity
Research Articles on ADAMTS6
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Products associated with ADAMTS6 blocking peptide
Pathways associated with ADAMTS6 blocking peptide
Diseases associated with ADAMTS6 blocking peptide
Organs/Tissues associated with ADAMTS6 blocking peptide
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