NP_149105
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24,592 Da
NCBI Official Full Name
zinc finger CCHC-type and RNA-binding motif-containing protein 1
NCBI Official Synonym Full Names
zinc finger CCHC-type and RNA binding motif 1
NCBI Official Synonym Symbols
MADP1; RBM36; MADP-1; SNRNP31; ZCCHC19 [Similar Products]
NCBI Protein Information
zinc finger CCHC-type and RNA-binding motif-containing protein 1; U11/U12-31K; U11/U12 snRNP 31K; U11/U12 snRNP 31 kDa protein; U11/U12 small nuclear ribonucleoprotein 31 kDa protein
UniProt Protein Name
Zinc finger CCHC-type and RNA-binding motif-containing protein 1
UniProt Synonym Protein Names
U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12-31K
UniProt Synonym Gene Names
UniProt Entry Name
ZCRB1_HUMAN
NCBI Summary for ZCRB1
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]
UniProt Comments for ZCRB1
ZCRB1: Up-regulated by morphine. Down-regulated at 30-36 degrees Celsius while it is up-regulated at 39 degrees Celsius. Component of the U11/U12 snRNPs that are part of the U12- type spliceosome.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 12q12
Cellular Component: nucleoplasm; U12-dependent spliceosome
Molecular Function: zinc ion binding; nucleotide binding
Biological Process: RNA splicing; mRNA processing
Research Articles on ZCRB1
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Organs/Tissues associated with ZCRB1 blocking peptide
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