NP_938080
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,833 Da
NCBI Official Full Name
polypeptide N-acetylgalactosaminyltransferase 10
NCBI Official Synonym Full Names
polypeptide N-acetylgalactosaminyltransferase 10
NCBI Official Synonym Symbols
GALNACT10; PPGALNACT10; PPGANTASE10 [Similar Products]
NCBI Protein Information
polypeptide N-acetylgalactosaminyltransferase 10; GalNAc transferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
UniProt Protein Name
Polypeptide N-acetylgalactosaminyltransferase 10
UniProt Synonym Protein Names
Polypeptide GalNAc transferase 10; GalNAc-T10; pp-GaNTase 10; Protein-UDP acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10
UniProt Synonym Gene Names
UniProt Entry Name
GLT10_HUMAN
NCBI Summary for GALNT10
This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010]
UniProt Comments for GALNT10
GALNT10: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Transferase; Glycan Metabolism - O-glycan biosynthesis; EC 2.4.1.41; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5q33.2
Cellular Component: Golgi membrane; integral to membrane
Molecular Function: polypeptide N-acetylgalactosaminyltransferase activity; metal ion binding; carbohydrate binding
Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification
Research Articles on GALNT10
Precautions
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Pathways associated with GALNT10 blocking peptide
Diseases associated with GALNT10 blocking peptide
Organs/Tissues associated with GALNT10 blocking peptide
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