EAW77638.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,239 Da
NCBI Official Full Name
lactamase, beta, isoform CRA_b
NCBI Official Synonym Full Names
lactamase beta
NCBI Official Synonym Symbols
NCBI Protein Information
serine beta-lactamase-like protein LACTB, mitochondrial
UniProt Protein Name
Serine beta-lactamase-like protein LACTB, mitochondrial
NCBI Summary for LACTb
This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic function. Increased expression of the related mouse gene was found to be associated with obesity. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Dec 2013]
UniProt Comments for LACTb
LACTB: a protein from the large 39S subunit of the mitochondrial ribosome (mitoribosome). The encoded protein has some sequence similarity to prokaryotic beta-lactamases but most of the residues that are responsible for the beta-lactamase activity are not conserved between the two proteins. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2010]
Protein type: EC 3.4.-.-; Mitochondrial; Protease
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component: cytosol; mitochondrion
Molecular Function: identical protein binding; peptidase activity
Biological Process: lipid metabolic process; proteolysis; regulation of lipid metabolic process
Research Articles on LACTb
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Products associated with anti-LACTb antibody
Diseases associated with anti-LACTb antibody
Organs/Tissues associated with anti-LACTb antibody
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