NP_683754.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,833 Da
NCBI Official Full Name
transcription factor E2F4
NCBI Official Synonym Full Names
E2F transcription factor 4
NCBI Protein Information
transcription factor E2F4
UniProt Protein Name
Transcription factor E2F4
UniProt Synonym Gene Names
UniProt Entry Name
E2F4_MOUSE
UniProt Comments for E2F4
E2F4: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Belongs to the E2F/DP family.
Protein type: DNA-binding
Cellular Component: cytoplasm; nuclear chromatin; nucleoplasm; nucleus; transcription factor complex
Molecular Function: DNA binding; protein binding; protein domain specific binding; transcription factor activity; transcription factor binding
Biological Process: blood circulation; cell cycle; cell projection organization and biogenesis; cell volume homeostasis; cilium biogenesis; epithelial cell development; G1/S-specific transcription in mitotic cell cycle; mitotic cell cycle; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of cell size; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on E2F4
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Products associated with E2F4 blocking peptide
Pathways associated with E2F4 blocking peptide
Diseases associated with E2F4 blocking peptide
Organs/Tissues associated with E2F4 blocking peptide
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