NP_003349.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,854 Da
NCBI Official Full Name
ceramide glucosyltransferase
NCBI Official Synonym Full Names
UDP-glucose ceramide glucosyltransferase
NCBI Official Synonym Symbols
NCBI Protein Information
ceramide glucosyltransferase; GLCT-1; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase
UniProt Protein Name
Ceramide glucosyltransferase
UniProt Synonym Protein Names
GLCT-1; Glucosylceramide synthase; GCS; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase
UniProt Synonym Gene Names
UniProt Entry Name
CEGT_HUMAN
NCBI Summary for UGCG
Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation. [provided by RefSeq, Oct 2009]
UniProt Comments for UGCG
UGCG: Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a flippase. Belongs to the glycosyltransferase 2 family.
Protein type: Lipid Metabolism - sphingolipid; EC 2.4.1.80; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of Human Ortholog: 9q31
Cellular Component: Golgi membrane; membrane; integral to membrane
Molecular Function: ceramide glucosyltransferase activity
Biological Process: epidermis development; sphingolipid metabolic process; glycosphingolipid biosynthetic process; glycosphingolipid metabolic process; glucosylceramide biosynthetic process
Research Articles on UGCG
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Products associated with anti-UGCG antibody
Pathways associated with anti-UGCG antibody
Diseases associated with anti-UGCG antibody
Organs/Tissues associated with anti-UGCG antibody
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