NP_001001520.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
hepatoma-derived growth factor-related protein 2 isoform 1
NCBI Protein Information
hepatoma-derived growth factor-related protein 2
UniProt Protein Name
Hepatoma-derived growth factor-related protein 2
UniProt Synonym Protein Names
Hepatoma-derived growth factor 2; HDGF-2
UniProt Synonym Gene Names
UniProt Entry Name
HDGR2_HUMAN
NCBI Summary for HDGFRP2
This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
UniProt Comments for HDGFRP2
HDGF2: a member of the hepatoma-derived growth factor (HDGF) family. Two alternatively spliced transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleoplasm; mitochondrion; nucleus
Molecular Function: DNA binding; chromatin binding
Biological Process: transcription, DNA-dependent
Product References and Citations for anti-HDGFRP2 antibody
Matsuoka, S., et al. Science 316(5828):1160-1166(2007) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Olsen, J.V., et al. Cell 127(3):635-648(2006) Vandegraaff, N., et al. Virology 346(2):415-426(2006) Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Research Articles on HDGFRP2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-HDGFRP2 antibody
Organs/Tissues associated with anti-HDGFRP2 antibody
|