NP_001287907.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Fanconi anemia core complex-associated protein 24 isoform 2
NCBI Official Synonym Full Names
Fanconi anemia core complex associated protein 24
NCBI Official Synonym Symbols
NCBI Protein Information
Fanconi anemia core complex-associated protein 24
UniProt Protein Name
Fanconi anemia core complex-associated protein 24
UniProt Synonym Protein Names
Fanconi anemia-associated protein of 24 kDa
UniProt Entry Name
FAP24_HUMAN
NCBI Summary for FAAP24
FAAP24 is a component of the Fanconi anemia (FA) core complex (see MIM 227650), which plays a crucial role in DNA damage response (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]
UniProt Comments for FAAP24
FAAP24: Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
Protein type: DNA repair, damage
Chromosomal Location of Human Ortholog: 19q13.11
Cellular Component: nucleoplasm; intracellular membrane-bound organelle
Molecular Function: protein binding; DNA binding; chromatin binding
Biological Process: DNA repair
Product References and Citations for anti-FAAP24 antibody
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ciccia A.,et al.Mol. Cell 25:331-343(2007).
Research Articles on FAAP24
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Products associated with anti-FAAP24 antibody
Pathways associated with anti-FAAP24 antibody
Diseases associated with anti-FAAP24 antibody
Organs/Tissues associated with anti-FAAP24 antibody
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