Q9NZI7.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,453 Da
NCBI Official Full Name
Upstream-binding protein 1
NCBI Official Synonym Full Names
upstream binding protein 1 (LBP-1a)
NCBI Protein Information
upstream-binding protein 1
UniProt Protein Name
Upstream-binding protein 1
UniProt Synonym Protein Names
Transcription factor LBP-1
UniProt Synonym Gene Names
UniProt Entry Name
UBIP1_HUMAN
UniProt Comments for UBP1
UBP1: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. Belongs to the grh/CP2 family. CP2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 3p22.3
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: DNA binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity
Biological Process: negative regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; viral genome replication
Research Articles on UBP1
Precautions
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Disclaimer
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Products associated with UBP1 blocking peptide
Diseases associated with UBP1 blocking peptide
Organs/Tissues associated with UBP1 blocking peptide
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