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DBR1 cdna clone

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Catalog # MBS1278874
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
DBR1 cdna clone
Product Name

DBR1, cDNA Clone

Popular Item
Full Product Name

DBR1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgcgggtgg ctgtggctgg ctgctgccac ggcgagctgg ataagatcta tgagacgctg gcgctggcag agcggcgcgg cccggggcct gtcgacctct tgctgtgctg cggcgacttc caggcggtgc gcaacgaggc ggatctacgc tgcatggccg tgccgcccaa gtatcgtcac atgcaaacct tctacaggta ttactctgga gagaaaaagg ctccagttct cacgctcttc attgggggaa accatgaagc ctcaaatcat ttgcaagagt taccctatgg tggctgggtg gcaccaaaca tttattattt aggtttggct ggtgtggtaa aataccgagg tgtaaggatc ggtggaatct ctggtatctt taaatctcat gactatcgaa aaggtcattt tgagtgcccc ccttataatt catctacaat caggagtata tatcatgtga gaaatattga agtctataaa ttaaaacagc tgaagcagcc tatagatata ttcttgtctc atgattggcc aagaagtata tatcattatg gaaataagaa gcaacttctt aagactaaat cttttttccg acaagaagtg gaaaataaca cattaggaag tccagctgcc tcagagcttt tagagcatct caaacctact tattggtttt ctgcccacct tcatgtgaag tttgccgcct tgatgcagca tcaggcaaag gataaaggac agacagccag agcaaccaaa tttttagcct tggacaaatg cttaccacat agagattttc ttcagatatt agagatagaa catgacccca gtgctcctga ttacttggaa tatgatattg aatggctcac tattctcagg gctacggatg atcttattaa tgtgactggg cgcctgtgga atatgccaga aaataatggc ctgcatgcaa ggtgggatta tagtgcaaca gaagaaggta tgaaagaagt attggaaaaa ttgaatcatg atctcaaggt tccatgtaac tttagtgtaa cagctgcttg ttatgatcct agcaagccac agacacaaat gcagctgatt cataggatca atcctcagac tactgaattt tgtgcccaac ttggcatcat agacatcaat gttaggcttc agaagtccaa ggaagaacat catgtgtgtg gtgaatatga agaacaggat gatgtggaga gtaatgactc tggagaagac cagagtgaat ataatacaga cacatctgct ctgtcttcta ttaatccaga tgaaataatg ttagatgaag aagaagatga agatagtatt gtaagtgcac atagtggcat gaatacacca tcggtagaac cttctgatca agcttctgag ttttctgcaa gtttctctga tgtcaggatc ttgccaggct ctatgattgt atcttctgat gatacggtgg attccacaat tgatagagag gggaaacctg gtgggactgt ggagtcaggg aatggagagg acttaaccaa ggtgccattg aagaggctga gtgatgaaca tgaacctgaa caaagaaaga aaattaagag gaggaatcaa gccatttacg ctgcagtgga tgatgatgat gatgatgcag cttaa
OMIM
607024
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of DBR1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for DBR1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
35,022 Da
NCBI Official Full Name
Homo sapiens debranching enzyme homolog 1 (S. cerevisiae), mRNA
NCBI Official Synonym Full Names
debranching RNA lariats 1
NCBI Official Symbol
NCBI Protein Information
lariat debranching enzyme
UniProt Protein Name
Lariat debranching enzyme
Protein Family
UniProt Gene Name
UniProt Entry Name
DBR1_HUMAN
NCBI Summary for DBR1
The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication. [provided by RefSeq, Nov 2011]
UniProt Comments for DBR1
DBR1: Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via a RNA lariat intermediate in cDNA synthesis. Belongs to the lariat debranching enzyme family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; RNA processing; Hydrolase; EC 3.1.-.-

Chromosomal Location of Human Ortholog: 3q22.3

Cellular Component: nucleus

Molecular Function: RNA lariat debranching enzyme activity

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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