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DECR2 recombinant protein :: 2,4-Dienoyl CoA Reductase 2 Recombinant Protein

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Catalog # MBS145258
Unit / Price
  0.002 mg  /  $140 +1 FREE 8GB USB
  0.01 mg  /  $205 +1 FREE 8GB USB
  1 mg  /  $5,015 +6 FREE 8GB USB
DECR2 recombinant protein
Product Name

2,4-Dienoyl CoA Reductase 2 (DECR2), Recombinant Protein

Full Product Name

Recombinant Human 2,4-Dienoyl CoA Reductase 2

Product Synonym Names
DECR2 Human; 2,4-Dienoyl CoA Reductase 2 Human Recombinant; Peroxisomal 2; 4-dienoyl-CoA reductase; pDCR; 2; 4-dienoyl-CoA reductase 2; DECR2; PDCR; SDR17C1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MGSSHHH HHH SSGLVPRGSH MGSMAQ PPPD VEGDDCLPAY RHLFCPDLLR DKVAFITGGG SGIGFRIAEI FMRHGCHTVI ASRSLPRVLT AARKLAGATG RRCLPLSMDV RAPPAVMAAV DQALKEFGRI DILINCAAGN FLCPAGALSF NAFKTVMDID TSGTFNVSRV LYEKFFRDHG GVIVNITATL GNRGQALQVH AGSAKAAVDA MTRHLAVEWG PQNIRVNSLA PGPISGTEGL RRLGGPQASL STKVTASPLQ RLGNKTEIAH SVLYLASPLA SYVTGAVLVA DGGAWLTFPN GVKGLPDFAS FSAKL.
OMIM
615839
3D Structure
ModBase 3D Structure for Q9NUI1
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
The DECR2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.15M NaCl and 1mM DTT.
Sterile Filtered colorless solution.
Other Notes
Small volumes of DECR2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
DECR2 recombinant protein
Description: DECR2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 315 amino acids (1-292) and having a molecular mass of 33.2kDa.DECR2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: Peroxisomal 2,4-dienoyl-CoA reductase (DECR2) is an supporting enzyme of beta-oxidation. DECR2 partakes in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. DECR2 catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
NCBI/Uniprot data below describe general gene information for DECR2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,589 Da
NCBI Official Full Name
peroxisomal 2,4-dienoyl-CoA reductase
NCBI Official Synonym Full Names
2,4-dienoyl CoA reductase 2, peroxisomal
NCBI Official Symbol
DECR2  [Similar Products]
NCBI Official Synonym Symbols
PDCR; SDR17C1
  [Similar Products]
NCBI Protein Information
peroxisomal 2,4-dienoyl-CoA reductase; 2,4-dienoyl-CoA reductase 2; short chain dehydrogenase/reductase family 17C, member 1
UniProt Protein Name
Peroxisomal 2,4-dienoyl-CoA reductase
UniProt Synonym Protein Names
2,4-dienoyl-CoA reductase 2
UniProt Gene Name
DECR2  [Similar Products]
UniProt Synonym Gene Names
PDCR; pDCR  [Similar Products]
UniProt Entry Name
DECR2_HUMAN
UniProt Comments for DECR2
DECR2: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.3.1.34; Oxidoreductase

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: peroxisomal membrane

Molecular Function: 2,4-dienoyl-CoA reductase (NADPH) activity; receptor binding; trans-2-enoyl-CoA reductase (NADPH) activity

Biological Process: unsaturated fatty acid biosynthetic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with DECR2 recombinant protein
Diseases associated with DECR2 recombinant protein
 Disease Name  Pubmed Publications
 Weight Gain Antibodies  >1 publications with DECR2 and Weight Gain
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