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DEF6 cdna clone

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Catalog # MBS1270657
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
DEF6 cdna clone
Product Name

DEF6, cDNA Clone

Popular Item
Full Product Name

DEF6 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggccctgc gcaaggaact gctcaagtcc atctggtacg cctttaccgc gctggacgtg gagaagagtg gcaaagtctc caagtcccag ctcaaggtgc tgtcccacaa cctgtacacg gtcctgcaca tcccccatga ccccgtggcc ctggaggaac acttccgaga tgatgatgac ggccctgtgt ccagccaggg atacatgccc tacctcaaca agtacatcct ggacaaggtg gaggaggggg cttttgttaa agagcacttt gatgagctgt gctggacgct gacggccaag aagaactatc gggcagatag caacgggaac agtatgctct ccaatcagga tgccttccgc ctctggtgcc tcttcaactt cctgtctgag gacaagtacc ctctgatcat ggttcctgat gaggtggaat acctgctgaa aaaggtactc agcagcatga gcttggaggt gagcttgggt gagctggagg agcttctggc ccaggaggcc caggtggccc agaccaccgg ggggctcagc gtctggcagt tcctggagct cttcaattcg ggccgctgcc tgcggggcgt gggccgggac accctcagca tggccatcca cgaggtctac caggagctca tccaagatgt cctgaagcag ggctacctgt ggaagcgagg gcacctgaga aggaactggg ccgaacgctg gttccagctg cagcccagct gcctctgcta ctttgggagt gaagagtgca aagagaaaag gggcattatc ccgctggatg cacactgctg cgtggaggtg ctgccagacc gcgacggaaa gcgctgcatg ttctgtgtga agacagccac ccgcacgtat gagatgagcg cctcagacac gcgccagcgc caggagtgga cagctgccat ccagatggcg atccggctgc aggccgaggg gaagacgtcc ctacacaagg acctgaagca gaaacggcgc gagcagcggg agcagcggta g
OMIM
610094
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of DEF6 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for DEF6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
73,910 Da
NCBI Official Full Name
Homo sapiens differentially expressed in FDCP 6 homolog (mouse), mRNA
NCBI Official Synonym Full Names
DEF6, guanine nucleotide exchange factor
NCBI Official Symbol
NCBI Official Synonym Symbols
IBP; SLAT; SWAP70L
  [Similar Products]
NCBI Protein Information
differentially expressed in FDCP 6 homolog
UniProt Protein Name
Differentially expressed in FDCP 6 homolog
UniProt Synonym Protein Names
IRF4-binding protein
UniProt Gene Name
UniProt Synonym Gene Names
IBP; DEF-6  [Similar Products]
UniProt Entry Name
DEFI6_HUMAN
NCBI Summary for DEF6
DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM, Mar 2008]
UniProt Comments for DEF6
DEF6: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling.

Protein type: GEFs, Rac/Rho; GEFs

Chromosomal Location of Human Ortholog: 6p21.33-p21.1

Cellular Component: membrane

Molecular Function: protein binding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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