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DEF6 peptide :: IBP / DEF6 Peptide

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Catalog # MBS425424
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
DEF6 peptide
Product Name

IBP / DEF6, Peptide

Also Known As

IBP / DEF6 Immunizing Peptide

Product Synonym Names
DEF6; IBP; differentially expressed in FDCP 6 homolog; RP3-329A5.5; SLAT; IRF4-binding protein; OTTHUMP00000016251; differentially expressed in FDCP 6 homolog (mouse); SWAP70L; SWAP-70-like adaptor protein of T cells; IBP / DEF6
Product Gene Name
Product Synonym Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
631
Sequence
ALRKELLKSI WYA-C
OMIM
610094
Species Reactivity
Human, Mouse, Rat, Dog, Pig, Cow
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of DEF6 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for DEF6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
73,910 Da
NCBI Official Full Name
differentially expressed in FDCP 6 homolog
NCBI Official Synonym Full Names
DEF6, guanine nucleotide exchange factor
NCBI Official Symbol
NCBI Official Synonym Symbols
IBP; SLAT; SWAP70L
  [Similar Products]
NCBI Protein Information
differentially expressed in FDCP 6 homolog
UniProt Protein Name
Differentially expressed in FDCP 6 homolog
UniProt Synonym Protein Names
IRF4-binding protein
UniProt Gene Name
UniProt Synonym Gene Names
IBP; DEF-6  [Similar Products]
UniProt Entry Name
DEFI6_HUMAN
NCBI Summary for DEF6
DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM, Mar 2008]
UniProt Comments for DEF6
DEF6: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling.

Protein type: GEFs; GEFs, Rac/Rho

Chromosomal Location of Human Ortholog: 6p21.33-p21.1

Cellular Component: cytoskeleton; filopodium; membrane; nucleus; perinuclear region of cytoplasm; plasma membrane

Molecular Function: protein binding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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