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DEFB2 recombinant protein :: BD-2 Recombinant Protein

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Catalog # MBS845421
Unit / Price
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  0.02 mg  /  $230 +1 FREE 8GB USB
  1 mg  /  $3,630 +4 FREE 8GB USB
DEFB2 recombinant protein
Product Name

BD-2 (DEFB2), Recombinant Protein

Popular Item
Full Product Name

BD-2, human recombinant

Product Synonym Names
Skin-antimicrobial peptide 1; SAP1; Beta-defensin 2; Defensin; beta 2; Skin-antimicrobial peptide 1; DEFB4A; DEFB102; DEFB2; DEFB4; DEFB4B
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602215
3D Structure
ModBase 3D Structure for O15263
Host
E Coli
Purity/Purification
>98% by SDS-PAGE and HPLC analyses Endotoxin level is <0.1 ng per ug (1EU/ug)
Form/Format
Sterile filtered and lyophilized with no additives
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers or store at 4°C for 1 week or -20°C for future use.
Biological activity
Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10-100 ng/mL.
Preparation and Storage
The lyophilized protein is best stored desiccated below 0°C. Reconstituted human BD-2 should be stored at working aliquots at -20°C.
Other Notes
Small volumes of DEFB2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
DEFB2 recombinant protein
Background: Recombinant human beta-defensin-2 (BD-2) is an antimicrobial peptide which belongs to the distinct family of beta-defensins. Recombinant human BD-2 is a 4.3 kDa protein containing 41 amino acid residues.
Applications Tested/Suitable for DEFB2 recombinant protein
SDS-PAGE; HPLC
NCBI/Uniprot data below describe general gene information for DEFB2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
4.3 kDa
NCBI Official Full Name
beta-defensin 4B
NCBI Official Synonym Full Names
defensin, beta 4B
NCBI Official Symbol
DEFB4B  [Similar Products]
NCBI Official Synonym Symbols
DEFB4P
  [Similar Products]
NCBI Protein Information
beta-defensin 4B
UniProt Protein Name
Beta-defensin 4A
UniProt Synonym Protein Names
Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1; SAP1
UniProt Gene Name
DEFB4A  [Similar Products]
UniProt Synonym Gene Names
DEFB102; DEFB2; DEFB4; BD-2; hBD-2; SAP1  [Similar Products]
UniProt Entry Name
DFB4A_HUMAN
NCBI Summary for DEFB2
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014]
UniProt Comments for DEFB2
defensin, beta 2: Has antibacterial activity (Potential). Belongs to the beta-defensin family. LAP/TAP subfamily.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: Golgi lumen; extracellular region

Biological Process: G-protein coupled receptor protein signaling pathway; defense response to bacterium; innate immune response; immune response; chemotaxis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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