NP_055671.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
163,847 Da
NCBI Official Full Name
DENN domain-containing protein 4B
NCBI Official Synonym Full Names
DENN/MADD domain containing 4B
NCBI Official Synonym Symbols
NCBI Protein Information
DENN domain-containing protein 4B
UniProt Protein Name
DENN domain-containing protein 4B
UniProt Synonym Gene Names
UniProt Entry Name
DEN4B_HUMAN
UniProt Comments for DENND4B
DENND4B: a Golgi-associated guanine nucleotide exchange factor (GEF) that activates RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
Protein type: GEFs; GEFs, Rab
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: nucleoplasm; Golgi apparatus; nucleus
Molecular Function: Rab guanyl-nucleotide exchange factor activity
Biological Process: regulation of Rab protein signal transduction
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