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DNAJB4 cdna clone

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Catalog # MBS1278642
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
DNAJB4 cdna clone
Product Name

DNAJB4, cDNA Clone

Popular Item
Also Known As

DNAJB4 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1014
Sequence
atggggaaag actattattg cattttggga attgagaaag gagcttcaga tgaagatatt aaaaaggctt accgaaaaca agccctcaaa tttcatccgg acaagaacaa atctcctcag gcagaggaaa aatttaaaga ggtcgcagaa gcttatgaag tattgagtga tcctaaaaag agagaaatat atgatcagtt tggggaggaa gggttgaaag gaggagcagg aggtactgat ggacaaggag gtaccttccg gtacaccttt catggcgatc ctcatgctac atttgctgca tttttcggag ggtccaaccc ctttgaaatt ttctttggaa gacgaatggg tggtggtaga gattctgaag aaatggaaat agatggtgat ccttttagtg cctttggttt cagcatgaat ggatatccaa gagacaggaa ttctgtgggg ccatcccgcc tcaaacaaga tcctccagtt attcatgaac ttagagtatc acttgaagag atatatagtg gttgtaccaa acggatgaag atttctcgaa aaaggctaaa cgctgatgga aggagttaca gatctgagga caaaattctt accattgaga ttaaaaaagg gtggaaagaa ggcaccaaaa ttacttttcc aagagaagga gatgaaacac caaatagtat tccagcagac attgttttta tcattaaaga caaagatcat ccaaaattta aaagggatgg atcaaatata atttatactg ctaaaattag tttacgagag gcattgtgtg gctgctcaat taatgtacca acactggatg gaagaaacat acctatgtca gtaaatgata ttgtgaaacc cggaatgagg agaagaatta ttggatatgg gctgccattt ccaaaaaatc ctgaccaacg tggtgacctt ctaatagaat ttgaggtgtc cttcccagat actatatctt cttcatccaa agaagtactt aggaaacatc ttcctgcctc atag
OMIM
611327
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of DNAJB4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for DNAJB4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,807 Da
NCBI Official Full Name
Homo sapiens DnaJ (Hsp40) homolog, subfamily B, member 4, mRNA
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member B4
NCBI Official Symbol
DNAJB4  [Similar Products]
NCBI Official Synonym Symbols
DjB4; HLJ1; DNAJW
  [Similar Products]
NCBI Protein Information
dnaJ homolog subfamily B member 4
UniProt Protein Name
DnaJ homolog subfamily B member 4
UniProt Synonym Protein Names
Heat shock 40 kDa protein 1 homolog; HSP40 homolog; Heat shock protein 40 homolog; Human liver DnaJ-like protein
Protein Family
UniProt Gene Name
DNAJB4  [Similar Products]
UniProt Synonym Gene Names
DNAJW; HLJ1; HSP40 homolog; Heat shock protein 40 homolog  [Similar Products]
UniProt Entry Name
DNJB4_HUMAN
NCBI Summary for DNAJB4
The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
UniProt Comments for DNAJB4
DNAJB4: Probable chaperone. Homodimer. The C-terminal section interacts with the C- terminal tail of OPRM1. Interacts also with SDIM1. By heat shock. Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 1p31.1

Cellular Component: cytoplasm; cytosol; nucleoplasm; plasma membrane

Molecular Function: chaperone binding; protein binding

Biological Process: response to heat; response to unfolded protein
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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