NP_001935.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
107,533 Da
NCBI Official Full Name
desmoglein-3 preproprotein
NCBI Official Synonym Full Names
desmoglein 3
NCBI Official Synonym Symbols
NCBI Protein Information
desmoglein-3
UniProt Protein Name
Desmoglein-3
UniProt Synonym Protein Names
130 kDa pemphigus vulgaris antigen; PVA; Cadherin family member 6
UniProt Synonym Gene Names
NCBI Summary for DSG3
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
UniProt Comments for DSG3
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Research Articles on DSG3
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Products associated with DSG3 elisa kit
Pathways associated with DSG3 elisa kit
Diseases associated with DSG3 elisa kit
Organs/Tissues associated with DSG3 elisa kit
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