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DYNLT1 recombinant protein :: Dynein light chain Tctex-type 1 (DYNLT1) Recombinant Protein

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Catalog # MBS951809
Unit / Price
  0.05 mg (E-Coli)  /  $505 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $675 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $745 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $830 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $910 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,025 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,045 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,045 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,065 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,515 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,555 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,630 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,030 +2 FREE 8GB USB
DYNLT1 recombinant protein
Product Name

Dynein light chain Tctex-type 1 (DYNLT1), Recombinant Protein

Also Known As

Recombinant Human Dynein light chain Tctex-type 1 (DYNLT1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-113aa, Full length protein
Sequence Length
113
Sequence
MEDYQAAEET AFVVDEVSNI VKEAIESAIG GNAYQHSKVN QWTTNVVEQT LSQLTKLGKP FKYIVTCVIM QKNGAGLHTA SSCFWDSSTD GSCTVRWENK TMYCIVSAFG LSI
OMIM
601554
3D Structure
ModBase 3D Structure for P63172
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of DYNLT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for DYNLT1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,452 Da
NCBI Official Full Name
dynein light chain Tctex-type 1 isoform 1
NCBI Official Synonym Full Names
dynein light chain Tctex-type 1
NCBI Official Symbol
DYNLT1  [Similar Products]
NCBI Official Synonym Symbols
CW-1; TCTEL1; tctex-1
  [Similar Products]
NCBI Protein Information
dynein light chain Tctex-type 1
UniProt Protein Name
Dynein light chain Tctex-type 1
UniProt Synonym Protein Names
Protein CW-1; T-complex testis-specific protein 1 homolog
Protein Family
UniProt Gene Name
DYNLT1  [Similar Products]
UniProt Synonym Gene Names
TCTEL1; TCTEX-1; TCTEX1  [Similar Products]
NCBI Summary for DYNLT1
This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
UniProt Comments for DYNLT1
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. May also be a accessory component of axonemal dynein.Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation (). Unrelated to the role in retrograde microtubule-associated movement may play a role in the dimerization of cytoplasmic proteins/domains such as for ACVR2B. Binds to the cytoplasmic domain of ACVR2B and, in vitro, inhibits ACVR2B signaling (PubMed:27502274).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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