NP_004206.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,466 Da
NCBI Official Full Name
receptor-binding cancer antigen expressed on SiSo cells
NCBI Official Synonym Full Names
estrogen receptor binding site associated, antigen, 9
NCBI Official Synonym Symbols
NCBI Protein Information
receptor-binding cancer antigen expressed on SiSo cells
UniProt Protein Name
Receptor-binding cancer antigen expressed on SiSo cells
UniProt Synonym Protein Names
Cancer-associated surface antigen RCAS1; Estrogen receptor-binding fragment-associated gene 9 protein
UniProt Synonym Gene Names
UniProt Entry Name
RCAS1_HUMAN
NCBI Summary for EBAG9
This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013]
UniProt Comments for EBAG9
RCAS1: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1- beta converting enzyme (ICE)-like proteases. Homodimer. By estrogen. Widely expressed. Expressed in ovary, testis, prostate, thymus, muscle and heart, but not in small intestine, colon, lymph nodes, or peripherical blood lymphocytes. The protein is not detected in any of the above organs.
Protein type: Membrane protein, integral; Apoptosis
Chromosomal Location of Human Ortholog: 8q23
Cellular Component: Golgi membrane; integral to membrane; secretory granule
Molecular Function: apoptotic protease activator activity
Biological Process: apoptosis; regulation of cell growth
Research Articles on EBAG9
Precautions
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Products associated with EBAG9 blocking peptide
Diseases associated with EBAG9 blocking peptide
Organs/Tissues associated with EBAG9 blocking peptide
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