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ECE2 cdna clone

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Catalog # MBS1266214
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
ECE2 cdna clone
Product Name

ECE2, cDNA Clone

Full Product Name

ECE2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcctctc caggggcagg tagggcgcct ccggagttac cggagcggaa ctgcgggtac cgcgaagtcg agtactggga tcagcgctac caaggcgcag ccgattctgc cccctacgat tggttcgggg acttctcctc cttccgtgcc ctcctagagc cggagctgcg gcccgaggac cgtatccttg tgctaggttg cgggaacagt gccctgagct acgagctgtt cctcggaggc ttccctaatg tgaccagtgt ggactactca tcagtcgtgg tggctgccat gcaggctcgc tatgcccatg tgccgcagct gcgctgggag accatggatg tgcggaagct ggacttcccc agtgcttctt ttgatgtggt gctcgagaag ggcacgctgg atgccctgct ggctggggaa cgagatccct ggaccgtgtc ctctgaaggt gtccacactg tggaccaggt gttgagtgag gtgagccgcg tgcttgtccc tggaggccgg tttatctcaa tgacttctgc tgccccccac tttcggacca gacactatgc ccaagcctat tatggctggt ccctgaggca tgctacctat ggcagcggtt tccacttcca tctctacctc atgcacaagg gcgggaagct cagtgtggcc cagctggctc tgggggccca aatcctctca ccccccagac ctcccacctc accttgcttc cttcaggact cagatcatga ggacttcctt agtgccattc agctctga
OMIM
610145
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ECE2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ECE2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
91,211 Da
NCBI Official Full Name
Homo sapiens endothelin converting enzyme 2, mRNA
NCBI Official Synonym Full Names
endothelin converting enzyme 2
NCBI Official Symbol
NCBI Protein Information
endothelin-converting enzyme 2
UniProt Protein Name
Endothelin-converting enzyme 2
UniProt Gene Name
UniProt Synonym Gene Names
KIAA0604; ECE-2  [Similar Products]
UniProt Entry Name
ECE2_HUMAN
NCBI Summary for ECE2
This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for ECE2
ECE2: Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta- amyloid peptide accumulation in brain. May also have methyltransferase activity. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Methyltransferase; Methyltransferase, protein arginine, predicted; Protease; Vesicle; Membrane protein, integral; EC 3.4.24.71

Chromosomal Location of Human Ortholog: 3q27.1

Cellular Component: cytoplasmic vesicle membrane

Molecular Function: metalloendopeptidase activity; protein binding

Biological Process: brain development; cardioblast differentiation; cell-cell signaling; heart development; peptide hormone processing
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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