NP_004083.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,387 Da
NCBI Official Full Name
enoyl-CoA hydratase, mitochondrial
NCBI Official Synonym Full Names
enoyl-CoA hydratase, short chain 1
NCBI Official Synonym Symbols
NCBI Protein Information
enoyl-CoA hydratase, mitochondrial
UniProt Protein Name
Enoyl-CoA hydratase, mitochondrial
UniProt Synonym Protein Names
Enoyl-CoA hydratase 1; Short-chain enoyl-CoA hydratase; SCEH
UniProt Synonym Gene Names
NCBI Summary for ECHS1
The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. [provided by RefSeq, Jul 2008]
UniProt Comments for ECHS1
Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. Has high substrate specificity for crotonyl-CoA and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA and methacrylyl-CoA. It is noteworthy that binds tiglyl-CoA, but hydrates only a small amount of this substrate.
Research Articles on ECHS1
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Products associated with anti-ECHS1 antibody
Pathways associated with anti-ECHS1 antibody
Diseases associated with anti-ECHS1 antibody
Organs/Tissues associated with anti-ECHS1 antibody
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