Name: EEF2 cdna clone-BC126259
Brand: MyBioSource
Price: 470 USD

Product Name

EEF2, cDNA Clone

Full Product Name

EEF2 cDNA Clone

Product Gene Name

EEF2 cdna clone

[Similar Products]

Research Use Only

For Research Use Only. Not for use in diagnostic procedures.

atggtgaact tcacggtaga ccagatccgc gccatcatgg acaagaaggc caacatccgc aacatgtctg tcatcgccca cgtggaccat ggcaagtcca cgctgacaga ctccctggtg tgcaaggcgg gcatcatcgc ctcggcccgg gccggggaga cacgcttcac tgatacccgg aaggacgagc aggagcgttg catcaccatc aagtcaactg ccatctccct cttctacgag ctctcggaga atgacttgaa cttcatcaag cagagcaagg acggtgccgg cttcctcatc aacctcattg actcccccgg gcatgtcgac ttctcctcgg aggtgactgc tgccctccga gtcaccgatg gcgcattggt ggtggtggac tgcgtgtcag gcgtgtgcgt gcagacggag acagtgctgc ggcaggccat tgccgagcgc atcaagcctg tgctgatgat gaacaagatg gaccgcgccc tgctggagct gcagctggag cccgaggagc tctaccagac tttccagcgc atcgtggaga acgtgaacgt catcatctcc acctacggcg agggcgagag cggccccatg ggcaacatca tgatcgatcc tgtcctcggt accgtgggct ttgggtctgg cctccacggg tgggccttca ccctgaagca gtttgccgag atgtatgtgg ccaagttcgc cgccaagggg gagggccagt tggggcctgc cgagcgggcc aagaaagtag aggacatgat gaagaagctg tggggtgaca ggtactttga cccagccaac ggcaagttca gcaagtcagc caccagcccc gaagggaaga agctgccacg caccttctgc cagctgatcc tggaccccat cttcaaggtg tttgatgcga tcatgaattt caagaaagag gagacagcaa aactgataga gaaactggac atcaaactgg acagcgagga caaggacaaa gaaggcaaac ccctgctgaa ggctgtgatg cgccgctggc tgcctgccgg agacgccttg ttgcagatga tcaccatcca cctgccctcc cctgtgacgg cccagaagta ccgctgcgag ctcctgtacg aggggccccc ggacgacgag gctgccatgg gcattaaaag ctgtgacccc aaaggccctc ttatgatgta tatttccaaa atggtgccaa cctccgacaa aggtcggttc tacgcctttg gacgagtctt ctcggggctg gtctccactg gcctgaaggt caggatcatg gggcccaact atacccctgg gaagaaggag gacctctacc tgaagccaat ccagagaaca atcttgatga tgggccgcta cgtggagccc atcgaggatg tgccttgtgg gaacattgtg ggcctcgtgg gcgtggacca gttcctggtg aagacgggca ccatcaccac cttcgagcac gcgcacaaca tgcgggtgat gaagttcagc gtcagccctg ttgtcagagt ggccgtggag gccaagaacc cggctgacct gcccaagctg gtggaggggc tgaagcggct ggccaagtcc gaccccatgg tgcagtgcat catcgaggag tcgggagagc acatcatcgc gggcgccggc gagctgcacc tggagatctg cctgaaggac ctggaggagg accacgcctg catccccatc aagaaatctg acccggtcgt ctcgtaccgc gagacggtca gtgaagagtc gaacgtgctc tgcctctcca agtcccccaa caagcacaac cggctgtaca tgaaggcgcg gcccttcccc gacggcctgg ccgaggacat cgataaaggc gaggtgtccg cccgtcagga gctcaagcag cgggcgcgct acctggccga gaagtacgag tgggacgtgg ctgaggcccg caagatctgg tgctttgggc ccgacggcac cggccccaac atcctcaccg acatcaccaa gggtgtgcag tacctcaacg agatcaagga cagtgtggtg gccggcttcc agtgggccac caaggagggc gcactgtgtg aggagaacat gcggggtgtg cgcttcgacg tccacgacgt caccctgcac gccgacgcca tccaccgcgg agggggccag atcatcccca cagcacggcg ctgcctctac gccagtgtgc tgaccgccca gccacgcctc atggagccca tctaccttgt ggagatccag tgtccagagc aggtggtcgg tggcatctac ggggttttga acaggaagcg gggccacgtg ttcgaggagt cccaggtggc cggcaccccc atgtttgtgg tcaaggccta tctgcccgtc aacgagtcct ttggcttcac cgctgacctg aggtccaaca cgggcggcca ggcgttcccc cagtgtgtgt ttgaccactg gcagatcctg cccggagacc ccttcgacaa cagcagccgc cccagccagg tggtggcgga gacccgcaag cgcaagggcc tgaaagaagg catccctgcc ctggacaact tcctggacaa attgtag

OMIM

130610

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of EEF2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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NCBI/Uniprot data below describe general gene information for EEF2. It may not necessarily be applicable to this product.

NCBI GI #

116496672

NCBI GeneID

1938

NCBI Accession #

BC126259 [Other Products]

UniProt Secondary Accession #

Q58J86; B2RMP5; D6W618[Other Products]

UniProt Related Accession #

P13639[Other Products]

Molecular Weight

95,338 Da

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NCBI Official Full Name

Homo sapiens eukaryotic translation elongation factor 2, mRNA

NCBI Official Synonym Full Names

eukaryotic translation elongation factor 2

NCBI Official Symbol

EEF2 [Similar Products]

NCBI Official Synonym Symbols

EF2; EF-2; EEF-2; SCA26

[Similar Products]

NCBI Protein Information

elongation factor 2

UniProt Protein Name

Elongation factor 2

Protein Family

Elongation factor

UniProt Gene Name

EEF2 [Similar Products]

UniProt Synonym Gene Names

EF2; EF-2 [Similar Products]

UniProt Entry Name

EF2_HUMAN

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NCBI Summary for EEF2

This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]

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UniProt Comments for EEF2

EEF2: a member of the GTP-binding translation elongation factor family. An essential factor for protein synthesis. Promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by eEF2 kinase phosphorylation. eEF2 kinase is normally dependent on Ca2+ ions and calmodulin. eEF2 kinase can also be activated by PKA in response to elevated cAMP levels, which are generally increased in stress- or starvation-related conditions. A variety of treatments known to raise intracellular Ca2+ or cAMP levels have been shown to result in increased phosphorylation of eEF2, and thus to inhibit peptide-chain elongation.

Protein type: Translation; Translation elongation

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cell-cell adherens junction; cytoplasm; cytosol; extracellular matrix; membrane; nucleus; plasma membrane; ribonucleoprotein complex

Molecular Function: GTPase activity; protein binding; protein kinase binding

Biological Process: peptidyl-diphthamide biosynthetic process from peptidyl-histidine; positive regulation of translation; translational elongation

Disease: Spinocerebellar Ataxia 26

Research Articles on EEF2

1. nuclear localization of active eEF-2 depends upon its interaction with p53, as cells lacking p53 contain less active eEF-2 in the nuclear compartment

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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

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Pathways associated with EEF2 cdna clone

Products by Pathway	Pathway Diagram
AMPK Signaling Pathway antibodies	AMPK Signaling Pathway Diagram
BDNF Signaling Pathway antibodies	BDNF Signaling Pathway Diagram
Eukaryotic Translation Elongation Pathway antibodies	Eukaryotic Translation Elongation Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Peptide Chain Elongation Pathway antibodies	Peptide Chain Elongation Pathway Diagram
Translation Pathway antibodies	Translation Pathway Diagram
Translation Factors Pathway antibodies	Translation Factors Pathway Diagram
MTOR Signaling Pathway antibodies	MTOR Signaling Pathway Diagram

Diseases associated with EEF2 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>18 publications with EEF2 and Neoplasms
Hypertrophy Antibodies	>17 publications with EEF2 and Hypertrophy
Cardiovascular Diseases Antibodies	>11 publications with EEF2 and Cardiovascular Diseases
Carcinoma Antibodies	>10 publications with EEF2 and Carcinoma
Heart Diseases Antibodies	>7 publications with EEF2 and Heart Diseases
Necrosis Antibodies	>6 publications with EEF2 and Necrosis
Adenocarcinoma Antibodies	>6 publications with EEF2 and Adenocarcinoma
Inflammation Antibodies	>5 publications with EEF2 and Inflammation
Brain Diseases Antibodies	>5 publications with EEF2 and Brain Diseases
Drug Toxicity Antibodies	>5 publications with EEF2 and Drug Toxicity

Organs/Tissues associated with EEF2 cdna clone

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>85 publications with EEF2 and Muscle
Brain Antibodies	>32 publications with EEF2 and Brain
Blood Antibodies	>30 publications with EEF2 and Blood
Heart Antibodies	>24 publications with EEF2 and Heart
Liver Antibodies	>15 publications with EEF2 and Liver
Kidney Antibodies	>12 publications with EEF2 and Kidney
Vascular Antibodies	>8 publications with EEF2 and Vascular
Pancreas Antibodies	>7 publications with EEF2 and Pancreas
Lung Antibodies	>4 publications with EEF2 and Lung
Bone Antibodies	>4 publications with EEF2 and Bone

Catalog #	MBS1274810
Unit / Price	0.01 mg Plasmid + 0.2 mL Glycerol-Stock / $470 +1 FREE 8GB USB