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EEF2 cdna clone

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Catalog # MBS1274810
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $470 +1 FREE 8GB USB
EEF2 cdna clone
Product Name

EEF2, cDNA Clone

Full Product Name

EEF2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggtgaact tcacggtaga ccagatccgc gccatcatgg acaagaaggc caacatccgc aacatgtctg tcatcgccca cgtggaccat ggcaagtcca cgctgacaga ctccctggtg tgcaaggcgg gcatcatcgc ctcggcccgg gccggggaga cacgcttcac tgatacccgg aaggacgagc aggagcgttg catcaccatc aagtcaactg ccatctccct cttctacgag ctctcggaga atgacttgaa cttcatcaag cagagcaagg acggtgccgg cttcctcatc aacctcattg actcccccgg gcatgtcgac ttctcctcgg aggtgactgc tgccctccga gtcaccgatg gcgcattggt ggtggtggac tgcgtgtcag gcgtgtgcgt gcagacggag acagtgctgc ggcaggccat tgccgagcgc atcaagcctg tgctgatgat gaacaagatg gaccgcgccc tgctggagct gcagctggag cccgaggagc tctaccagac tttccagcgc atcgtggaga acgtgaacgt catcatctcc acctacggcg agggcgagag cggccccatg ggcaacatca tgatcgatcc tgtcctcggt accgtgggct ttgggtctgg cctccacggg tgggccttca ccctgaagca gtttgccgag atgtatgtgg ccaagttcgc cgccaagggg gagggccagt tggggcctgc cgagcgggcc aagaaagtag aggacatgat gaagaagctg tggggtgaca ggtactttga cccagccaac ggcaagttca gcaagtcagc caccagcccc gaagggaaga agctgccacg caccttctgc cagctgatcc tggaccccat cttcaaggtg tttgatgcga tcatgaattt caagaaagag gagacagcaa aactgataga gaaactggac atcaaactgg acagcgagga caaggacaaa gaaggcaaac ccctgctgaa ggctgtgatg cgccgctggc tgcctgccgg agacgccttg ttgcagatga tcaccatcca cctgccctcc cctgtgacgg cccagaagta ccgctgcgag ctcctgtacg aggggccccc ggacgacgag gctgccatgg gcattaaaag ctgtgacccc aaaggccctc ttatgatgta tatttccaaa atggtgccaa cctccgacaa aggtcggttc tacgcctttg gacgagtctt ctcggggctg gtctccactg gcctgaaggt caggatcatg gggcccaact atacccctgg gaagaaggag gacctctacc tgaagccaat ccagagaaca atcttgatga tgggccgcta cgtggagccc atcgaggatg tgccttgtgg gaacattgtg ggcctcgtgg gcgtggacca gttcctggtg aagacgggca ccatcaccac cttcgagcac gcgcacaaca tgcgggtgat gaagttcagc gtcagccctg ttgtcagagt ggccgtggag gccaagaacc cggctgacct gcccaagctg gtggaggggc tgaagcggct ggccaagtcc gaccccatgg tgcagtgcat catcgaggag tcgggagagc acatcatcgc gggcgccggc gagctgcacc tggagatctg cctgaaggac ctggaggagg accacgcctg catccccatc aagaaatctg acccggtcgt ctcgtaccgc gagacggtca gtgaagagtc gaacgtgctc tgcctctcca agtcccccaa caagcacaac cggctgtaca tgaaggcgcg gcccttcccc gacggcctgg ccgaggacat cgataaaggc gaggtgtccg cccgtcagga gctcaagcag cgggcgcgct acctggccga gaagtacgag tgggacgtgg ctgaggcccg caagatctgg tgctttgggc ccgacggcac cggccccaac atcctcaccg acatcaccaa gggtgtgcag tacctcaacg agatcaagga cagtgtggtg gccggcttcc agtgggccac caaggagggc gcactgtgtg aggagaacat gcggggtgtg cgcttcgacg tccacgacgt caccctgcac gccgacgcca tccaccgcgg agggggccag atcatcccca cagcacggcg ctgcctctac gccagtgtgc tgaccgccca gccacgcctc atggagccca tctaccttgt ggagatccag tgtccagagc aggtggtcgg tggcatctac ggggttttga acaggaagcg gggccacgtg ttcgaggagt cccaggtggc cggcaccccc atgtttgtgg tcaaggccta tctgcccgtc aacgagtcct ttggcttcac cgctgacctg aggtccaaca cgggcggcca ggcgttcccc cagtgtgtgt ttgaccactg gcagatcctg cccggagacc ccttcgacaa cagcagccgc cccagccagg tggtggcgga gacccgcaag cgcaagggcc tgaaagaagg catccctgcc ctggacaact tcctggacaa attgtag
OMIM
130610
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of EEF2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for EEF2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
95,338 Da
NCBI Official Full Name
Homo sapiens eukaryotic translation elongation factor 2, mRNA
NCBI Official Synonym Full Names
eukaryotic translation elongation factor 2
NCBI Official Symbol
NCBI Official Synonym Symbols
EF2; EF-2; EEF-2; SCA26
  [Similar Products]
NCBI Protein Information
elongation factor 2
UniProt Protein Name
Elongation factor 2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
EF2; EF-2  [Similar Products]
UniProt Entry Name
EF2_HUMAN
NCBI Summary for EEF2
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]
UniProt Comments for EEF2
EEF2: a member of the GTP-binding translation elongation factor family. An essential factor for protein synthesis. Promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by eEF2 kinase phosphorylation. eEF2 kinase is normally dependent on Ca2+ ions and calmodulin. eEF2 kinase can also be activated by PKA in response to elevated cAMP levels, which are generally increased in stress- or starvation-related conditions. A variety of treatments known to raise intracellular Ca2+ or cAMP levels have been shown to result in increased phosphorylation of eEF2, and thus to inhibit peptide-chain elongation.

Protein type: Translation; Translation elongation

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cell-cell adherens junction; cytoplasm; cytosol; extracellular matrix; membrane; nucleus; plasma membrane; ribonucleoprotein complex

Molecular Function: GTPase activity; protein binding; protein kinase binding

Biological Process: peptidyl-diphthamide biosynthetic process from peptidyl-histidine; positive regulation of translation; translational elongation

Disease: Spinocerebellar Ataxia 26
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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