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anti-EFNB2 antibody :: Ephrin-B2 Antibody

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Catalog # MBS856871
Unit / Price
  0.05 mg  /  $180 +1 FREE 8GB USB
  0.1 mg  /  $215 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Ephrin-B2 (EFNB2), Antibody

Full Product Name

Ephrin-B2 (Ab-330) Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P52799
Species Reactivity
Human, Mouse, Rat
Ephrin-B2 (Ab-330) antibody detects endogenous levels of total Ephrin-B2 protein.
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
The antiserum was produced against synthesized non-phosphopeptide derived from human Ephrin-B2 around the phosphorylation site of tyrosine 330 (N-I-YP-Y-K).
Preparation and Storage
Store at-20 degree C for 1 year
Other Notes
Small volumes of anti-EFNB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-EFNB2 antibody
Western Blot (WB)
Application Notes for anti-EFNB2 antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-EFNB2 antibody
Western blot analysis of extract from A431 cells untreated or treated with Insulin, using Ephrin-B2 (Ab-330) antibody.
anti-EFNB2 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for EFNB2. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,923 Da[Similar Products]
NCBI Official Full Name
NCBI Official Synonym Full Names
ephrin B2
NCBI Official Symbol
EFNB2  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
UniProt Protein Name
UniProt Synonym Protein Names
EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L
Protein Family
UniProt Gene Name
EFNB2  [Similar Products]
UniProt Synonym Gene Names
EPLG5; HTKL; LERK5; LERK-5; HTK-L  [Similar Products]
NCBI Summary for EFNB2
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]
UniProt Comments for EFNB2
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
Product References and Citations for anti-EFNB2 antibody
Chrencik JE, et al.(2006) J Biol Chem; 281(38):28185-28192. Kertesz N, et al. (2006) Blood; 107(6):2330-2338. Noren NK, et al. (2004) Proc Natl Acad Sci USA; 101(15):5583-5588.

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