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EFTUD2 elisa kit :: Bovine 116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) ELISA Kit

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Catalog # MBS7205188
Unit / Price
  48-Strip-Wells  /  $440 +1 FREE 8GB USB
  96-Strip-Wells  /  $640 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
EFTUD2 elisa kit
Product Name

116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2), ELISA Kit

Also Known As

Bovine 116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
gene 610536
Species Reactivity
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Assay Type
Competitive
Detection Range
100-2500pg/mL
Sensitivity
1.0pg/mL
Preparation and Storage
Store all reagents at 2-8 degree C.
Sample Preparation
We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of EFTUD2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forEFTUD2purchase
MBS7205188 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EFTUD2. The ELISA analytical biochemical technique of the MBS7205188 kit is based on EFTUD2 antibody-EFTUD2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EFTUD2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EFTUD2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Product Categories/Family for EFTUD2 elisa kit
NCBI/Uniprot data below describe general gene information for EFTUD2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
108,283 Da
NCBI Official Full Name
116 kDa U5 small nuclear ribonucleoprotein component isoform c
NCBI Official Synonym Full Names
elongation factor Tu GTP binding domain containing 2
NCBI Official Symbol
EFTUD2  [Similar Products]
NCBI Official Synonym Symbols
MFDM; MFDGA; Snu114; Snrp116; SNRNP116; U5-116KD
  [Similar Products]
NCBI Protein Information
116 kDa U5 small nuclear ribonucleoprotein component; hSNU114; SNU114 homolog; U5 snRNP-specific protein, 116 kDa; elongation factor Tu GTP-binding domain-containing protein 2
UniProt Protein Name
116 kDa U5 small nuclear ribonucleoprotein component
UniProt Synonym Protein Names
Elongation factor Tu GTP-binding domain-containing protein 2; SNU114 homolog; hSNU114; U5 snRNP-specific protein, 116 kDa; U5-116 kDa
UniProt Gene Name
EFTUD2  [Similar Products]
UniProt Synonym Gene Names
KIAA0031; SNRP116; hSNU114; U5-116 kDa  [Similar Products]
UniProt Entry Name
U5S1_HUMAN
NCBI Summary for EFTUD2
This gene encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
UniProt Comments for EFTUD2
EFTUD2: Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP. Defects in EFTUD2 are the cause of mandibulofacial dysostosis with microcephaly (MFDM). A rare syndrome characterized by progressive microcephaly, midface and malar hypoplasia, micrognathia, microtia, dysplastic ears, preauricular skin tags, significant developmental delay, and speech delay. Many patients have major sequelae, including choanal atresia that results in respiratory difficulties, conductive hearing loss, and cleft palate. Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Spliceosome; RNA splicing

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: nucleoplasm; spliceosome; Cajal body; membrane; cytoplasm; nuclear speck

Molecular Function: GTPase activity; protein binding; GTP binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA processing

Disease: Mandibulofacial Dysostosis, Guion-almeida Type
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withEFTUD2 elisa kit
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