• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ENA-78 recombinant protein :: ENA-78 / CXCL5 Recombinant Protein

Scan QR to view Datasheet
Catalog # MBS695999
Unit / Price
  0.005 mg  /  $125 +1 FREE 8GB USB
  0.02 mg  /  $195 +1 FREE 8GB USB
  0.1 mg  /  $505 +1 FREE 8GB USB
  0.5 mg  /  $1,410 +1 FREE 8GB USB
  1 mg  /  $2,320 +2 FREE 8GB USB
ENA-78 recombinant protein
Product Name

ENA-78 / CXCL5, Recombinant Protein

Popular Item
Also Known As

Human ENA-78 / CXCL5 (8-78 a.a.)

Product Synonym Names
Recombinant Human ENA-78 (CXCL5) (8-78 a.a.)
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
LRELRCVCL QTTQGVHPK MISNLQVFA IGPQCSKVE VVASLKNGK EICLDPEAP FLKKVIQKI LDGGNKEN
OMIM
600324
3D Structure
ModBase 3D Structure for P42830
Host
E Coli
Species Reactivity
Species Reactivity: Human
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Biological Activity
Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml.
Cell Type
Monocytes and Macrophages, Endothelial Cells
Preparation and Storage
At -20 degree C
Other Notes
Small volumes of ENA-78 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ENA-78 recombinant protein
ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. Three N-terminal truncated variants of human ENA-78; ENA 5-78, ENA 8-78, ENA 9-78, contain 74, 71, and 70 amino acid residues, respectively, possess increased biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant human ENA-78 is a 7.8 kDa protein consisting of 71 amino acid residues.
NCBI/Uniprot data below describe general gene information for ENA-78. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,972 Da
NCBI Official Full Name
C-X-C motif chemokine 5
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 5
NCBI Official Symbol
CXCL5  [Similar Products]
NCBI Official Synonym Symbols
SCYB5; ENA-78
  [Similar Products]
NCBI Protein Information
C-X-C motif chemokine 5; neutrophil-activating protein 78; neutrophil-activating peptide ENA-78; epithelial-derived neutrophil-activating protein 78; small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78)
UniProt Protein Name
C-X-C motif chemokine 5
UniProt Synonym Protein Names
ENA-78(1-78); Epithelial-derived neutrophil-activating protein 78; Neutrophil-activating peptide ENA-78; Small-inducible cytokine B5Cleaved into the following 2 chains:ENA-78(8-78); ENA-78(9-78)
UniProt Gene Name
CXCL5  [Similar Products]
UniProt Synonym Gene Names
ENA78; SCYB5  [Similar Products]
UniProt Entry Name
CXCL5_HUMAN
NCBI Summary for ENA-78
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]
UniProt Comments for ENA-78
CXCL5: Involved in neutrophil activation. In vitro, ENA-78(8- 78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; CXCR chemokine receptor binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; positive regulation of cell proliferation; neutrophil mediated immunity; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; signal transduction; chemotaxis; inflammatory response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000