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F11 elisa kit :: Mouse Coagulation factor XI ELISA Kit

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Catalog # MBS2881535
Unit / Price
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F11 elisa kit
Product Name

Coagulation factor XI (F11), ELISA Kit

Popular Item
Full Product Name

Mouse Coagulation factor XI ELISA Kit

Product Synonym Names
Coagulation factor XI; FXI; Plasma thromboplastin antecedent; PTA; F11; 3.4.21.27
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for Q91Y47
Species Reactivity
Assay Type
Sandwich
Detection Range
0.312-20 ng/mL
Sensitivity
0.09 ng/mL
Intra-Assay CV
<=5.2%
Inter-Assay CV
<=7.3%
Recovery
88%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of F11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for F11purchase
MBS2881535 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Coagulation factor XI (F11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing F11. The ELISA analytical biochemical technique of the MBS2881535 kit is based on F11 antibody-F11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect F11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, F11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for F11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
69,789 Da
NCBI Official Full Name
coagulation factor XI preproprotein
NCBI Official Synonym Full Names
coagulation factor XI
NCBI Official Symbol
NCBI Official Synonym Symbols
FXI; PTA; Cf11; AI503996; 1600027G01Rik
  [Similar Products]
NCBI Protein Information
coagulation factor XI
UniProt Protein Name
Coagulation factor XI
UniProt Synonym Protein Names
Plasma thromboplastin antecedent; PTA
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
FXI; PTA  [Similar Products]
UniProt Entry Name
FA11_MOUSE
NCBI Summary for F11
This gene encodes a glycoprotein coagulation factor that plays an important role in intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that can be activated by coagulation factor XIIa, thrombin or factor XIa to generate active factor XIa protease. Mice lacking the encoded protein display a survival advantage during peritoneal sepsis and resist inflammation and bacterial accumulation upon infection with Listeria. [provided by RefSeq, Apr 2015]
UniProt Comments for F11
F11: Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. Defects in F11 are the cause of factor XI deficiency (FA11D); also known as plasma thromboplastin antecedent deficiency or Rosenthal syndrome. It is a hemorrhagic disease characterized by reduced levels and activity of factor XI resulting in moderate bleeding symptoms, usually occurring after trauma or surgery. Patients usually do not present spontaneous bleeding but women can present with menorrhagia. Hemorrhages are usually moderate. Belongs to the peptidase S1 family. Plasma kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; EC 3.4.21.27; Protease

Cellular Component: extracellular region; extracellular space

Molecular Function: heparin binding; hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: blood coagulation; hemostasis; plasminogen activation; positive regulation of fibrinolysis; proteolysis; regulation of blood coagulation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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