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FAIM3 elisa kit :: Human Fas apoptotic inhibitory molecule 3 ELISA Kit

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Catalog # MBS903912
Unit / Price DISCONTINUED
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Typical Testing Data/Standard Curve (for reference only)
Product Name

Fas apoptotic inhibitory molecule 3 (FAIM3), ELISA Kit

Popular Item
Also Known As

Human Fas apoptotic inhibitory molecule 3, FAIM3 ELISA Kit

Product Synonym Names
Human Fas apoptotic inhibitory molecule 3 (FAIM3) ELISA kit; FcmR; TOSO; Fc mu receptor; IgM Fc receptor; immunoglobulin mu Fc receptor; regulator of Fas-induced apoptosis; Fas apoptotic inhibitory molecule 3
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
MBS903912 Testing Data
Sequence Length
278
OMIM
606015
3D Structure
ModBase 3D Structure for O60667
Species Reactivity
Specificity
This assay has high sensitivity and excellent specificity for detection of Human FAIM3. No significant cross-reactivity or interference between Human FAIM3 and analogues was observed.
Assay Type
Sandwich
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Detection Wavelength
450 nm
Sample Volume
50-100ul
Protein Biological Process 1
Immunity
Protein Biological Process 3
Immunity
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of FAIM3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forFAIM3purchase
MBS903912 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fas apoptotic inhibitory molecule 3 (FAIM3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FAIM3. The ELISA analytical biochemical technique of the MBS903912 kit is based on FAIM3 antibody-FAIM3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FAIM3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FAIM3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
FAIM3 elisa kit
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FAIM3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FAIM3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FAIM3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FAIM3 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Typical Testing Data/Standard Curve (for reference only) of FAIM3 elisa kit
FAIM3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS903912. Click to request current manual
NCBI/Uniprot data below describe general gene information for FAIM3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,146 Da
NCBI Official Full Name
fas apoptotic inhibitory molecule 3 isoform b
NCBI Official Synonym Full Names
Fas apoptotic inhibitory molecule 3
NCBI Official Symbol
FAIM3  [Similar Products]
NCBI Official Synonym Symbols
FCMR; TOSO
  [Similar Products]
NCBI Protein Information
fas apoptotic inhibitory molecule 3; Fc mu receptor; IgM Fc receptor; immunoglobulin mu Fc receptor; regulator of Fas-induced apoptosis Toso
UniProt Protein Name
Fas apoptotic inhibitory molecule 3
UniProt Synonym Protein Names
Regulator of Fas-induced apoptosis Toso
UniProt Gene Name
FAIM3  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
FAIM3_HUMAN
NCBI Summary for FAIM3
Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]
UniProt Comments for FAIM3
FAIM3: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: integral to membrane; extracellular region

Biological Process: immune system process; cellular defense response; negative regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with FAIM3 elisa kit
Organs/Tissues associated with FAIM3 elisa kit
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