NP_001269280.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
F-box/LRR-repeat protein 19 isoform 3
NCBI Official Synonym Full Names
F-box and leucine-rich repeat protein 19
NCBI Protein Information
F-box/LRR-repeat protein 19; jumonji C domain-containing histone demethylase 1C
UniProt Protein Name
F-box/LRR-repeat protein 19
UniProt Synonym Protein Names
F-box and leucine-rich repeat protein 19
UniProt Synonym Gene Names
UniProt Entry Name
FXL19_HUMAN
NCBI Summary for FBXL19
This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for FBXL19
FBXL19: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: SCF ubiquitin ligase complex
Molecular Function: DNA binding; zinc ion binding
Biological Process: proteasomal ubiquitin-dependent protein catabolic process
Research Articles on FBXL19
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Products associated with FBXL19 elisa kit
Diseases associated with FBXL19 elisa kit
Organs/Tissues associated with FBXL19 elisa kit
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