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FBXL3 peptide

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Catalog # MBS426579
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
FBXL3 peptide
Product Name

FBXL3, Peptide

Also Known As

FBXL3 Immunizing Peptide

Product Synonym Names
FBXL3; F-box and leucine-rich repeat protein 3; FBL3; FBL3A; FBXL3A; F-box and leucine-rich repeat protein 3A; F-box protein Fbl3a
Product Gene Name
Antibody/Peptide Pairs
FBXL3 peptide (MBS426579) is used for blocking the activity of FBXL3 antibody (MBS420338)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
428
Sequence
KRGGRDSDRN SSEE-C
OMIM
605653
Species Reactivity
Human, Mouse, Rat, Dog, Pig
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of FBXL3 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for FBXL3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,707 Da
NCBI Official Full Name
F-box/LRR-repeat protein 3
NCBI Official Synonym Full Names
F-box and leucine-rich repeat protein 3
NCBI Official Symbol
FBXL3  [Similar Products]
NCBI Official Synonym Symbols
FBL3; FBL3A; FBXL3A
  [Similar Products]
NCBI Protein Information
F-box/LRR-repeat protein 3
UniProt Protein Name
F-box/LRR-repeat protein 3
UniProt Synonym Protein Names
F-box and leucine-rich repeat protein 3A; F-box/LRR-repeat protein 3A
UniProt Gene Name
FBXL3  [Similar Products]
UniProt Synonym Gene Names
FBL3A; FBXL3A  [Similar Products]
UniProt Entry Name
FBXL3_HUMAN
NCBI Summary for FBXL3
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus. [provided by RefSeq, Jul 2008]
UniProt Comments for FBXL3
FBXL3: Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 13q22

Cellular Component: cytosol; nucleus; SCF ubiquitin ligase complex; ubiquitin ligase complex

Molecular Function: protein binding; ubiquitin-protein ligase activity

Biological Process: entrainment of circadian clock by photoperiod; protein destabilization; protein ubiquitination; regulation of circadian rhythm; rhythmic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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