NP_034314.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44.7 kDa
NCBI Official Full Name
high affinity immunoglobulin epsilon receptor subunit alpha
NCBI Official Synonym Full Names
Fc receptor, IgE, high affinity I, alpha polypeptide
NCBI Official Synonym Symbols
FcERI; Fce1a; Fcr-5; fcepsilonri [Similar Products]
NCBI Protein Information
high affinity immunoglobulin epsilon receptor subunit alpha
UniProt Protein Name
High affinity immunoglobulin epsilon receptor subunit alpha
UniProt Synonym Protein Names
Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha
UniProt Synonym Gene Names
UniProt Entry Name
FCERA_MOUSE
UniProt Comments for Fcer1a
FCER1A: Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Protein type: Membrane protein, integral
Cellular Component: cell surface; external side of plasma membrane; integral to plasma membrane; lipid raft
Molecular Function: IgE binding; IgE receptor activity; protein binding
Biological Process: activation of JNK activity; activation of MAPK activity; cell surface receptor linked signal transduction; leukotriene biosynthetic process; positive regulation of calcium-mediated signaling; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of interleukin-3 biosynthetic process; positive regulation of mast cell degranulation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of type I hypersensitivity; serotonin secretion; signal transduction
Research Articles on Fcer1a
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Products associated with Fcer1a recombinant protein
Pathways associated with Fcer1a recombinant protein
Diseases associated with Fcer1a recombinant protein
Organs/Tissues associated with Fcer1a recombinant protein
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