NP_963857.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
low affinity immunoglobulin gamma Fc region receptor II-c
NCBI Official Synonym Full Names
Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
NCBI Official Synonym Symbols
CD32; FCG2; CD32C; CDW32; IGFR2; FCRIIC [Similar Products]
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-c; fc-gamma-RIIc; IgG Fc receptor II-c; Fc gamma receptor IIC; immunoglobulin G Fc receptor II-c
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-c
UniProt Synonym Protein Names
CDw32; Fc-gamma RII-c; Fc-gamma-RIIc; FcRII-c; CD_antigen: CD32
UniProt Synonym Gene Names
CD32; FCG2; IGFR2; IgG Fc receptor II-c; Fc-gamma-RIIc; FcRII-c [Similar Products]
UniProt Entry Name
FCG2C_HUMAN
NCBI Summary for FCGR2C
This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012]
UniProt Comments for FCGR2C
FCGR2C: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed.
Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 1q23.3
Cellular Component: cytoplasm; integral to membrane; plasma membrane
Molecular Function: protein binding; transmembrane receptor activity; IgG binding
Biological Process: immune response; signal transduction
Disease: Thrombocytopenic Purpura, Autoimmune
Research Articles on FCGR2C
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Pathways associated with FCGR2C elisa kit
Diseases associated with FCGR2C elisa kit
Organs/Tissues associated with FCGR2C elisa kit
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