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FEZ1 cdna clone

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Catalog # MBS1273455
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
FEZ1 cdna clone
Product Name

FEZ1, cDNA Clone

Popular Item
Full Product Name

FEZ1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggaggccc cactggtgag tctggatgaa gagtttgagg accttcgacc ctcctgctcg gaggacccgg aggagaagcc ccagtgtttc tatggttcat ctccccacca tctcgaggac ccctccctct ccgagcttga gaatttttct tccgaaataa tcagcttcaa gtccatggag gacctcgtaa atgaatttga tgagaagctc aatgtctgct ttcggaacta caacgccaag accgagaacc tagctcccgt gaagaaccag ttacagatcc aagaggagga ggagaccctt caggacgagg aggtttggga tgctctgaca gacaattaca tcccttcact ctcagaagac tggagggatc caaacatcga ggctctgaat ggcaactgct ctgacactga gatccatgag aaagaagagg aagagttcaa tgagaagagt gaaaatgatt ccggtatcaa cgaggagcct ctgctcacag cagatcaggt aattgaggag attgaggaaa tgatgcagaa ctccccagac cctgaggaag aagaggaggt tctggaagaa gaggatggag gagaaacttc ctcccaggca gactcggtcc tcctgcagga gatgcaggca ttgacacaga ccttcaacaa caactggtcc tatgaagggc tgaggcacat gtctgggtct gagctgaccg agctgctgga ccaggtggag ggtgccatcc gtgacttctc ggaggagctg gtgcagcagc tggcccgccg ggacgagctg gagtttgaga aggaagtgaa gaactccttt atcacggtgc ttattgaggt tcagaacaag cagaaggagc agcgagaact gatgaaaaag aggcggaaag agaaagggct gagcctgcag agcagccgga tagagaaggg aaaccagatg cctctcaagc gcttcagcat ggaaggcatc tccaacattc tgcagagtgg catccgccag acctttggct cctcaggaac tgacaaacag tatctgaaca cagtcattcc ttacgagaag aaagcctctc ctccctcagt ggaagacctg cagatgctga caaacattct ctttgccatg aaggaggata atgagaaggt gcctactttg ctaacggact acattttaaa agtgctctgc cctacctaa
OMIM
604825
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of FEZ1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for FEZ1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,074 Da
NCBI Official Full Name
Homo sapiens fasciculation and elongation protein zeta 1 (zygin I), mRNA
NCBI Official Synonym Full Names
fasciculation and elongation protein zeta 1
NCBI Official Symbol
NCBI Official Synonym Symbols
UNC-76
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NCBI Protein Information
fasciculation and elongation protein zeta-1
UniProt Protein Name
Fasciculation and elongation protein zeta-1
UniProt Synonym Protein Names
Zygin I; Zygin-1
UniProt Gene Name
UniProt Entry Name
FEZ1_HUMAN
NCBI Summary for FEZ1
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for FEZ1
FEZ1: May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules. Belongs to the zygin family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 11q24.2

Cellular Component: cytoplasm; Golgi apparatus; microtubule cytoskeleton

Molecular Function: protein binding

Biological Process: axon guidance; cell adhesion; nervous system development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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