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FGF7 recombinant protein :: Keratinocyte Growth Factor (rHuKGF) Recombinant Protein

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Catalog # MBS197014
Unit / Price
  0.002 mg  /  $195 +1 FREE 8GB USB
  0.01 mg  /  $280 +1 FREE 8GB USB
  1 mg  /  $5,650 +7 FREE 8GB USB
FGF7 recombinant protein
Product Name

Keratinocyte Growth Factor (rHuKGF) (FGF7), Recombinant Protein

Also Known As

Recombinant Human Keratinocyte Growth Factor

Product Synonym Names
Recombinant Human Keratinocyte Growth Factor (rHuKGF)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 15; NC_000015.9 (49715375..49779523). Location: 15q21.2
OMIM
148180
3D Structure
ModBase 3D Structure for P21781
Host
E Coli
Specificity
Recombinant Human Keratinocyte Growth Factor (rHuKGF)
Purity/Purification
Greater than 97% by RP-HPLC, anion-exchange chromatography; reducing and non-reducing SDS-PAGE, silver stain.
Purification: Chromatographic
Form/Format
Sterile filtered, lyophilized.
Dimers/Aggregates
<1% by SDSPAGE
Biological Activity
Fully biologically active compared to reference standards. Specific Activity is 105 Units/mg.
Endotoxin Level
<0.1 ng/ug
Protein Content
Determined spectrophotometrically at 280nm (extinction coefficient 0.9) and by RPHPLC analysis against a calibrated standard.
Solubility
Reconstitute the lyophilized product in sterile water not less than 100 ug/ml.
Stabilizer
None
Preservatives
None
Preparation and Storage
Lyophilized product is stable at room temperature for 3 weeks. Store lyophilized product desiccated at -20 degree C. Upon reconstitution, store at 4 degree C for 2-7 days or aliquot and store at -20 degree C. For long-term storage add either HSA or BSA to 0.1%. Avoid repeated freeze-thaw cycles.
Other Notes
Small volumes of FGF7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FGF7 recombinant protein
Recombinant Human KGF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 164 amino acids with a molecular mass of 18,995 daltons. This product has full biological activity.
Product Categories/Family for FGF7 recombinant protein
NCBI/Uniprot data below describe general gene information for FGF7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
22,509 Da[Similar Products]
NCBI Official Full Name
keratinocyte growth factor
NCBI Official Synonym Full Names
fibroblast growth factor 7
NCBI Official Symbol
NCBI Official Synonym Symbols
KGF; HBGF-7
  [Similar Products]
NCBI Protein Information
keratinocyte growth factor; FGF-7; OTTHUMP00000162252; heparin-binding growth factor 7
UniProt Protein Name
Keratinocyte growth factor
UniProt Synonym Protein Names
Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
FGF7_HUMAN
NCBI Summary for FGF7
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq]
UniProt Comments for FGF7
FGF7: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Belongs to the heparin-binding growth factors family.

Protein type: Cytokine; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: Golgi apparatus; extracellular region

Molecular Function: heparin binding; protein binding; growth factor activity; chemoattractant activity; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of keratinocyte migration; epidermis development; hair follicle morphogenesis; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; mesenchymal cell proliferation; signal transduction; positive regulation of peptidyl-tyrosine phosphorylation; positive chemotaxis; positive regulation of cell division; positive regulation of cell proliferation; actin cytoskeleton reorganization; response to wounding; insulin receptor signaling pathway; innate immune response; positive regulation of epithelial cell proliferation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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