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FIt3 recombinant protein

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Catalog # MBS538273
Unit / Price
  0.002 mg  /  $180 +1 FREE 8GB USB
  0.01 mg  /  $310 +1 FREE 8GB USB
FIt3 recombinant protein
Product Name

FIt3, Recombinant Protein

Full Product Name

FIt3 Ligand protein (Mouse)

Product Synonym Names
Flt3; FLT3 protein; Flt-3; Flt-3 ligand; Fms-related tyrosine kinase 3 ligand protein; Flt-3 protein; Flt 3; Flt 3 protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Host
Mouse
Purity/Purification
> 98% pure
Form/Format
Lyophilized from 10mM Na3PO4, pH 7.8. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Protein Type
Recombinant
Biological Significance
FLT3 is a receptor tyrosine kinase with important roles in hematopoietic stem/progenitor cell survival and proliferation. It is mutated in about 1/3 of acute myeloid leukemia (AML) patients, either by internal tandem duplications (ITD) of the juxtamembrane domain or by point mutations usually involving the kinase domain (kDa).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of FIt3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FIt3 recombinant protein
Purified recombinant Mouse FIt3 Ligand protein
Applications Tested/Suitable for FIt3 recombinant protein
User optimized
NCBI/Uniprot data below describe general gene information for FIt3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,836 Da
NCBI Official Full Name
Fit3p
NCBI Official Symbol
NCBI Protein Information
Fit3p
UniProt Protein Name
Facilitator of iron transport 3
UniProt Gene Name
UniProt Entry Name
FIT3_YEAST
UniProt Comments for FIt3
Involved in the uptake of non-siderophore and siderohpore sources of iron. Has a role in the retention of iron in the cell wall and periplasmic space.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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