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FMO2 recombinant protein :: Dimethylaniline monooxygenase [N-oxide-forming] 2 (FMO2) Recombinant Protein

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Catalog # MBS1368677
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $890 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $960 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,190 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,190 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,295 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,315 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,430 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,470 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,720 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,990 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,230 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,310 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,330 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,440 +4 FREE 8GB USB
FMO2 recombinant protein
Product Name

Dimethylaniline monooxygenase [N-oxide-forming] 2 (FMO2), Recombinant Protein

Full Product Name

Recombinant Human Dimethylaniline monooxygenase [N-oxide-forming] 2 (FMO2)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-471aa, Full Length of Mature Protein
Sequence
AKKVAVIGAG VSGLISLKCC VDEGLEPTCF ERTEDIGGVW RFKENVEDGR ASIYQSVVTN TSKEMSCFSD FPMPEDFPNF LHNSKLLEYF RIFAKKFDLL KYIQFQTTVL SVRKCPDFSS SGQWKVVTQS NGKEQSAVFD AVMVCSGHHI LPHIPLKSFP GMERFKGQYF HSRQYKHPDG FEGKRILVIG MGNSGSDIAV ELSKNAAQVF ISTRHGTWVM SRISEDGYPW DSVFHTRFRS MLRNVLPRTA VKWMIEQQMN RWFNHENYGL EPQNKYIMKE PVLNDDVPSR LLCGAIKVKS TVKELTETSA IFEDGTVEEN IDVIIFATGY SFSFPFLEDS LVKVENNMVS LYKYIFPAHL DKSTLACIGL IQPLGSIFPT AELQARWVTR VFKGLCSLPS ERTMMMDIIK RNEKRIDLFG ESQSQTLQTN YVDYLDELAL EIGAKPDFCS LLFKDPKLAV RLYFGPCNSY
OMIM
603955
3D Structure
ModBase 3D Structure for Q99518
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of FMO2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FMO2 recombinant protein
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. This protein represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
NCBI/Uniprot data below describe general gene information for FMO2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,644 Da
NCBI Official Full Name
dimethylaniline monooxygenase
NCBI Official Synonym Full Names
flavin containing monooxygenase 2
NCBI Official Symbol
NCBI Official Synonym Symbols
FMO1B1
  [Similar Products]
NCBI Protein Information
dimethylaniline monooxygenase [N-oxide-forming] 2
UniProt Protein Name
Dimethylaniline monooxygenase [N-oxide-forming] 2
UniProt Synonym Protein Names
Dimethylaniline oxidase 2; FMO 1B1; Pulmonary flavin-containing monooxygenase 2; FMO 2
UniProt Gene Name
UniProt Synonym Gene Names
FMO 2  [Similar Products]
NCBI Summary for FMO2
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
UniProt Comments for FMO2
Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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