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FNTA elisa kit :: Human farnesyltransferase, CAAX box, alpha ELISA Kit

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Catalog # MBS9339744
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FNTA elisa kit
Product Name

farnesyltransferase, CAAX box, alpha (FNTA), ELISA Kit

Popular Item
Full Product Name

Human Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, FNTA ELISA Kit

Product Synonym Names
Human Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) ELISA kit; FPTA; MGC99680; PGGT1A; PTAR2; FTase-alpha; GGTase-I-alpha; farnesyltransferase alpha-subunit; protein prenyltransferase alpha subunit repeat containing 2; ras proteins prenyltransferase alpha; type I pr; farnesyltransferase; CAAX box; alpha
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
134635
3D Structure
ModBase 3D Structure for P49354
Species Reactivity
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
Serum, Plasma and Tissue Homogenate
Assay Type
Sandwich
Detection Range
3.12 ng/ml - 100 ng/ml.
Sensitivity
1.0 ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of FNTA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for FNTApurchase
MBS9339744 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the farnesyltransferase, CAAX box, alpha (FNTA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FNTA. The ELISA analytical biochemical technique of the MBS9339744 kit is based on FNTA antibody-FNTA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FNTA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FNTA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
FNTA elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FNTA (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
Sample Manual Insert of MBS9339744. Click to request current manual
NCBI/Uniprot data below describe general gene information for FNTA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,409 Da
NCBI Official Full Name
protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
NCBI Official Synonym Full Names
farnesyltransferase, CAAX box, alpha
NCBI Official Symbol
NCBI Official Synonym Symbols
FPTA; PTAR2; PGGT1A
  [Similar Products]
NCBI Protein Information
protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; FTase-alpha; GGTase-I-alpha; farnesyl-protein transferase alpha-subunit; ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase alpha subunit; protein prenyltransferase alpha subunit repeat containing 2
UniProt Protein Name
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
UniProt Synonym Protein Names
CAAX farnesyltransferase subunit alpha; FTase-alpha; Ras proteins prenyltransferase subunit alpha; Type I protein geranyl-geranyltransferase subunit alpha; GGTase-I-alpha
UniProt Gene Name
UniProt Synonym Gene Names
GGTase-I-alpha  [Similar Products]
UniProt Entry Name
FNTA_HUMAN
NCBI Summary for FNTA
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]
UniProt Comments for FNTA
FNTA: Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK. Belongs to the protein prenyltransferase subunit alpha family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.5.1.59; Transferase; EC 2.5.1.58

Chromosomal Location of Human Ortholog: 8p11

Cellular Component: microtubule associated complex; cytoplasm; cytosol

Molecular Function: protein binding; protein geranylgeranyltransferase activity; CAAX-protein geranylgeranyltransferase activity; microtubule binding; acetylcholine receptor regulator activity; receptor tyrosine kinase binding; alpha-tubulin binding; protein farnesyltransferase activity; Rab-protein geranylgeranyltransferase activity

Biological Process: rhodopsin mediated signaling; protein geranylgeranylation; phototransduction, visible light; protein farnesylation; regulation of rhodopsin mediated signaling; neurotransmitter receptor metabolic process; apoptosis; transforming growth factor beta receptor signaling pathway; regulation of receptor activity; cell structure disassembly during apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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