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FRZB elisa kit :: Mouse frizzled-related protein ELISA Kit

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Catalog # MBS937358 (SPECIAL PROMOTIONAL PRICING for a limited time)
Unit / Price
  24-Strip-Wells (LIMIT 1)  /  $240 +1 FREE 8GB USB
  48-Strip-Wells  /  $435 +1 FREE 8GB USB
  96-Strip-Wells  /  $625 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,595 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $4,905 +6 FREE 8GB USB
FRZB elisa kit
Product Name

frizzled-related protein (FRZB), ELISA Kit

Popular Item
Also Known As

Mouse Secreted frizzled-related protein 3, FRZB ELISA Kit

Product Synonym Names
Mouse Secreted frizzled-related protein 3 (FRZB) ELISA kit; FRE; FRITZ; FRP-3; FRZB-1; FRZB-PEN; FRZB1; FZRB; OS1; SFRP3; SRFP3; hFIZ; frizzled homolog-related; frizzled-related protein
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Sequence Length
323
3D Structure
ModBase 3D Structure for P97401
Species Reactivity
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse FRZB. No significant cross-reactivity or interference between Mouse FRZB and analogues was observed.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
Detection Wavelength
450 nm
Sample Volume
50-100ul
Protein Biological Process 1
Developmental Protein
Protein Biological Process 3
Differentiation
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of FRZB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forFRZBpurchase
MBS937358 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the frizzled-related protein (FRZB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FRZB. The ELISA analytical biochemical technique of the MBS937358 kit is based on FRZB antibody-FRZB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FRZB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FRZB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for FRZB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,011 Da
NCBI Official Full Name
secreted frizzled-related protein 3
NCBI Official Synonym Full Names
frizzled-related protein
NCBI Official Symbol
NCBI Official Synonym Symbols
Frp; Sfrp3; fritz; frzb-1; frezzled
  [Similar Products]
NCBI Protein Information
secreted frizzled-related protein 3; sFRP-3; frizzled-related protein 1; secreted frizzled-related sequence protein 3
UniProt Protein Name
Secreted frizzled-related protein 3
UniProt Synonym Protein Names
Frezzled; Fritz; Frizzled-related protein 1; FrzB-1
UniProt Gene Name
UniProt Synonym Gene Names
Fiz; Fre; Frzb1; Sfrp3; sFRP-3  [Similar Products]
UniProt Entry Name
SFRP3_MOUSE
UniProt Comments for FRZB
FRZB: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development. Defects in FRZB are associated with susceptibility to osteoarthritis type 1(OS1). Osteoarthritis is a degenerative disease of the joints characterized by degradation of the hyaline articular cartilage and remodeling of the subchondral bone with sclerosis. Clinical symptoms include pain and joint stiffness often leading to significant disability and joint replacement. Belongs to the secreted frizzled-related protein (sFRP) family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: Wnt-protein binding; protein binding

Biological Process: negative regulation of cell proliferation; inner ear morphogenesis; convergent extension involved in organogenesis; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; positive regulation of apoptosis; multicellular organismal development; positive regulation of fat cell differentiation; negative regulation of cell growth; cell differentiation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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