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FSCN2 peptide :: Fascin 2 Peptide

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Catalog # MBS425042
Unit / Price
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  0.1 mg  /  $190 +1 FREE 8GB USB
FSCN2 peptide
Product Name

Fascin 2 (FSCN2), Peptide

Full Product Name

Fascin 2 Immunizing Peptide

Product Synonym Names
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus); RFSN; RP30; fascin 2; retinal fascin; Fascin 2; Fascin 2
Product Gene Name
Antibody/Peptide Pairs
Fascin 2 peptide (MBS425042) is used for blocking the activity of Fascin 2 antibody (MBS420322)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
CHHRGSNQLD TNR
OMIM
607643
Species Reactivity
Human, Mouse, Rat, Dog
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of FSCN2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for FSCN2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2008 Certified Laboratory.NP_036550.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,381 Da
NCBI Official Full Name
fascin-2 isoform 2
NCBI Official Synonym Full Names
fascin actin-bundling protein 2, retinal
NCBI Official Symbol
FSCN2  [Similar Products]
NCBI Official Synonym Symbols
RFSN; RP30
  [Similar Products]
NCBI Protein Information
fascin-2
UniProt Protein Name
Fascin-2
UniProt Synonym Protein Names
Retinal fascin
Protein Family
UniProt Gene Name
FSCN2  [Similar Products]
UniProt Entry Name
FSCN2_HUMAN
NCBI Summary for FSCN2
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FSCN2
FSCN2: Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Defects in FSCN2 are the cause of retinitis pigmentosa type 30 (RP30). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30 inheritance is autosomal dominant. Belongs to the fascin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: actin cytoskeleton; cytoplasm; stereocilium

Molecular Function: actin binding; actin filament binding; protein binding, bridging

Biological Process: actin cytoskeleton organization and biogenesis; actin filament bundle formation; anatomical structure morphogenesis; eye photoreceptor cell development; visual perception

Disease: Retinitis Pigmentosa 30
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with FSCN2 peptide
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