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FuR recombinant protein :: Ferric uptake regulator (FuR) Recombinant Protein

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Catalog # MBS203197
Unit / Price
  0.1 mg  /  $310 +1 FREE 8GB USB
  0.5 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

Ferric uptake regulator (FuR), Recombinant Protein

Popular Item
Also Known As

Ferric uptake regulator (FuR), 1-148aa, E Coli, E Coli

Product Synonym Names
DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport; Ferric uptake regulator; FuR; ECK0671; Ferric uptake regulation protein; JW0669.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
148
Sequence
MTDNNTALKK AGLKVTLPRL KILEVLQEPD NHHVSAEDLY KRLIDMGEEI GLATVYRVLN QFDDAGIVTR HNFEGGKSVF ELTQQHHHDH LICLDCGKVI EFSDDSIEAR QREIAAKHGI RLTNHSLYLY GHCAEGDCRE DEHAHEGK
3D Structure
ModBase 3D Structure for P0A9A9
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid in 20mM Tris pH 8.0, 2mM CaCl2, 100mM NaCl
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of FuR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FuR recombinant protein
Fur (ferric uptake regulator) protein is a DNA-binding protein which regulates iron-responsive genes. Fur is a small, 17-kDa, global transcriptional repressor that in the presence of iron regulates functions as diverse as iron acquisition, oxidative stress, and virulence. In Escherichia coli, members of the Fur family regulate the expression of more than 100 genes that function in processes as varied as the biosynthesis and transport of siderophores, the expression of virulence factors, the alleviation of oxidative and NO-induced stress, and the inhibition of ferritin production through the expression of RyhB. Recombinant FuR was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for FuR recombinant protein
Applications Tested/Suitable for FuR recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for FuR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
16.7kDa (148aa), confirmed by MALDI-TOF.
NCBI Official Full Name
ferric iron uptake regulon transcriptional repressor; autorepressor
NCBI Official Symbol
NCBI Official Synonym Symbols
ECK0671; JW0669
  [Similar Products]
NCBI Protein Information
ferric iron uptake regulon transcriptional repressor; autorepressor
UniProt Protein Name
Ferric uptake regulation protein
UniProt Gene Name
UniProt Synonym Gene Names
Ferric uptake regulator  [Similar Products]
NCBI Summary for FuR
Fur translation in coupled to the translation of the upstream leader pepidie Uof; Uof translation is inhibited by the antisense sRNA ryhB; Uof translation opens up a hairpin that blocks Fur translation (Vecerek, 2007). [More information is available at EcoGene: EG10359].
UniProt Comments for FuR
Acts as a global negative controlling element, employing Fe2+ as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon.
Product References and Citations for FuR recombinant protein
O'Sullivan DJ., et al. (1994). FEMS Microbiol Lett. Apr 15; 117 (3):327-32; Mills SA., et al. (2005) Biochemistry. Oct 18; 44 (41):13553-9;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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