NP_032002.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
247,230 Da
NCBI Official Full Name
coagulation factor V
NCBI Official Synonym Full Names
coagulation factor V
NCBI Protein Information
coagulation factor V; activated protein C cofactor
UniProt Protein Name
Coagulation factor V
UniProt Synonym Protein Names
Activated protein C cofactorCleaved into the following 2 chains:Coagulation factor V heavy chain; Coagulation factor V light chain
UniProt Entry Name
FA5_MOUSE
NCBI Summary for FV
This gene encodes a glycoprotein coagulation factor that plays a critical role in the process of blood coagulation and hemostasis. The encoded protein is activated by thrombin, to generate a heterodimer containing heavy and light chains held together by calcium ions. About half of the mice lacking the encoded protein die at an embryonic stage possible due to abnormal yolk-sac vasculature while the remaining animals succumbed to massive hemorrhage immediately after birth. A point mutation in this gene has been shown to cause disseminated intravascular thrombosis in the perinatal period, resulting in frequent deaths of newborn mice. [provided by RefSeq, Apr 2015]
UniProt Comments for FV
Function: Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.
Enzyme regulation: Inhibited by SERPINA5
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Products associated with FV elisa kit
Pathways associated with FV elisa kit
Diseases associated with FV elisa kit
Organs/Tissues associated with FV elisa kit
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