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FXYD2 recombinant protein :: Sodium/potassium-transporting ATPase subunit gamma Recombinant Protein

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Catalog # MBS7042773
Unit / Price
  0.01 mg  /  $675 +1 FREE 8GB USB
  0.05 mg  /  $1,175 +1 FREE 8GB USB
  0.1 mg  /  $2,100 +2 FREE 8GB USB
FXYD2 recombinant protein
Product Name

Sodium/potassium-transporting ATPase subunit gamma (FXYD2), Recombinant Protein

Full Product Name

Sodium/potassium-transporting ATPase subunit gamma

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-66aa; full length protein
Sequence
MTGLSMDGGG SPKGDVDPFY YDYETVRNGG LIFAGLAFIV GLLILLSRRF RCGGNKKRRQ INEDEP
OMIM
154020
3D Structure
ModBase 3D Structure for P54710
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol.
Tag Information
Tag type will be determined during the manufacturing process.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of FXYD2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FXYD2 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Product Categories/Family for FXYD2 recombinant protein
NCBI/Uniprot data below describe general gene information for FXYD2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7,355 Da
NCBI Official Full Name
sodium/potassium-transporting ATPase subunit gamma isoform 1
NCBI Official Synonym Full Names
FXYD domain containing ion transport regulator 2
NCBI Official Symbol
FXYD2  [Similar Products]
NCBI Official Synonym Symbols
HOMG2; ATP1G1
  [Similar Products]
NCBI Protein Information
sodium/potassium-transporting ATPase subunit gamma
UniProt Protein Name
Sodium/potassium-transporting ATPase subunit gamma
UniProt Synonym Protein Names
FXYD domain-containing ion transport regulator 2; Sodium pump gamma chain
UniProt Gene Name
FXYD2  [Similar Products]
UniProt Synonym Gene Names
ATP1C; ATP1G1; Na(+)/K(+) ATPase subunit gamma  [Similar Products]
UniProt Entry Name
ATNG_HUMAN
NCBI Summary for FXYD2
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes the sodium/potassium-transporting ATPase subunit gamma. Mutations in this gene have been associated with Renal Hypomagnesemia-2. Alternatively spliced transcript variants have been described. Read-through transcripts have been observed between this locus and the upstream FXYD domain-containing ion transport regulator 6 (FXYD6, GeneID 53826) locus.[provided by RefSeq, Feb 2011]
UniProt Comments for FXYD2
FXYD2: May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. Defects in FXYD2 are the cause of hypomagnesemia type 2 (HOMG2); also known as dominant renal hypomagnesemia or hypomagnesemia with hypocalciuria. HOMG2 is a disorder due to primary renal wasting of magnesium. Plasma levels of other electrolytes are normal. The only abnormality found, in addition to low magnesium levels, is lowered renal excretion of calcium resulting in hypocalciuria. Belongs to the FXYD family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: plasma membrane; sodium:potassium-exchanging ATPase complex

Molecular Function: sodium channel regulator activity; transporter activity

Biological Process: transport

Disease: Hypomagnesemia 2, Renal
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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