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GABRA5 cdna clone

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Catalog # MBS1277184
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
GABRA5 cdna clone
Product Name

GABRA5, cDNA Clone

Also Known As

GABRA5 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1389
Sequence
atggacaatg gaatgttctc tggttttatc atgatcaaaa acctccttct cttttgtatt tccatgaact tatccagtca ctttggcttt tcacagatgc caaccagttc agtgaaagat gagaccaatg acaacatcac gatatttacc aggatcttgg atgggctctt ggatggctac gacaacagac ttcggcccgg gctgggagag cgcatcactc aggtgaggac cgacatctac gtcaccagct tcggcccggt gtccgacacg gaaatggagt acaccataga cgtgtttttc cgacaaagct ggaaagatga aaggcttcgg tttaaggggc ccatgcagcg cctccctctc aacaacctcc ttgccagcaa gatctggacc ccagacacgt tcttccacaa cgggaagaag tccatcgctc acaacatgac cacgcccaac aagctgctgc ggctggagga cgacggcacc ctgctctaca ccatgcgctt gaccatctct gcagagtgcc ccatgcagct tgaggacttc ccgatggatg cgcacgcttg ccctctgaaa tttggcagct atgcgtaccc taattctgaa gtcgtctacg tctggaccaa cggctccacc aagtcggtgg tggtggcgga agatggctcc agactgaacc agtaccacct gatggggcag acggtgggca ctgagaacat cagcaccagc acaggcgaat acacaatcat gacagctcac ttccacctga aaaggaagat tggctacttt gtcatccaga cctaccttcc ctgcataatg accgtgatct tatcacaggt gtccttttgg ctgaaccggg aatcagtccc agccaggaca gtttttgggg tcaccacggt gctgaccatg acgaccctca gcatcagcgc caggaactct ctgcccaaag tggcctacgc caccgccatg gactggttca tagccgtgtg ctatgccttc gtcttctcgg cgctgataga gtttgccacg gtcaattact ttaccaagag aggctgggcc tgggatggca aaaaagcctt ggaagcagcc aagatcaaga aaaagcgtga agtcatacta aataagtcaa caaacgcttt tacaactggg aagatgtctc accccccaaa cattccgaag gaacagaccc cagcagggac gtcgaataca acctcagtct cagtaaaacc ctctgaagag aagacttctg aaagcaaaaa gacttacaac agtatcagca aaattgacaa aatgtcccga atcgtattcc cagtcttgtt cggcactttc aacttagttt actgggcaac gtatttgaat agggagccgg tgataaaagg agccgcctct ccaaaataa
OMIM
137142
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of GABRA5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for GABRA5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
52,146 Da
NCBI Official Full Name
Homo sapiens cDNA clone IMAGE:3868411, **** WARNING: chimeric clone ****
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor alpha5 subunit
NCBI Official Symbol
GABRA5  [Similar Products]
NCBI Protein Information
gamma-aminobutyric acid receptor subunit alpha-5
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit alpha-5
UniProt Synonym Protein Names
GABA(A) receptor subunit alpha-5
UniProt Gene Name
GABRA5  [Similar Products]
UniProt Entry Name
GBRA5_HUMAN
NCBI Summary for GABRA5
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for GABRA5
GABRA5: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA5 sub-subfamily.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, ion channel; Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: GABA-A receptor activity; receptor activity; transporter activity

Biological Process: positive regulation of defense response to virus by host; signal transduction; transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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