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GAL80 peptide

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Catalog # MBS633737
Unit / Price
  1 mg  /  $570 +1 FREE 8GB USB
GAL80 peptide
Product Name

Gal80, Peptide

Also Known As

Gal80

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: XIII; NC_001145.3 (171594..172901). Location: chromosome: XIII
3D Structure
ModBase 3D Structure for P04387
Purity/Purification
0.8
Form/Format
Supplied as a lyophilized powder.
Sequence (linear)
DERGNRLGQRVPKTVC
Quality Control
HPLC, MS
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of GAL80 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GAL80 peptide
The Gal80p complex consists of three components encoded by GAL4,GAL80, and Gal3. These components form a herterotrimeric complex. S. cerevisiae responds to galactose as sole carbon source by activating the GAL genes. The switch from expressed to activated gene expression involves the interplay of three proteins: the activator Gal4p, the repressor Gal80p, the inducer Gal3p, and two small molecules ATP and galactose. In the absence of galactose the transcriptional activity of Gal4p is inhibited by Gal80p. The association of galactose and ATP with Gal3p promote its interaction with the Gal4p -Gal80p complex. This interaction allows Gal4p to be freed from Gal80p inhibition and activate transcription. It has also been shown that Gal1p can also relieve the Gal80 repression of Gal4p in the presence of galactose, although less efficiently than Gal3p.
Product Categories/Family for GAL80 peptide
NCBI/Uniprot data below describe general gene information for GAL80. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,323 Da[Similar Products]
NCBI Official Full Name
Gal80p
NCBI Official Symbol
GAL80  [Similar Products]
NCBI Protein Information
Gal80p
UniProt Protein Name
Galactose/lactose metabolism regulatory protein GAL80
UniProt Gene Name
GAL80  [Similar Products]
UniProt Entry Name
GAL80_YEAST
UniProt Comments for GAL80
Function: This protein is a negative regulator for the gene expression of the lactose/galactose metabolic genes. It binds to GAL4 and so blocks transcriptional activation by it, in the absence of an inducing sugar. Ref.4

Subunit structure: Monomer. Ref.4

Miscellaneous: Present with 784 molecules/cell in log phase SD medium.

Sequence similarities: To K.lactis GAL80.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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