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GCGR peptide :: Glucogon receptor Peptide

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Catalog # MBS425484
Unit / Price
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  0.1 mg  /  $190 +1 FREE 8GB USB
GCGR peptide
Product Name

Glucogon receptor (GCGR), Peptide

Full Product Name

Glucogon receptor Immunizing Peptide

Product Synonym Names
GCGR; glucagon receptor; GGR; MGC138246; Glucogon receptor; Glucogon receptor
Product Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
C-HGPPSKEL QFGR
OMIM
138033
Species Reactivity
Human
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of GCGR peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for GCGR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,009 Da
NCBI Official Full Name
glucagon receptor
NCBI Official Synonym Full Names
glucagon receptor
NCBI Official Symbol
NCBI Official Synonym Symbols
GGR; GL-R
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NCBI Protein Information
glucagon receptor
UniProt Protein Name
Glucagon receptor
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
GLR_HUMAN
NCBI Summary for GCGR
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]
UniProt Comments for GCGR
GCGR: This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 2

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: endosome; integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: glucagon receptor activity; guanyl-nucleotide exchange factor activity; peptide hormone binding

Biological Process: cell surface receptor linked signal transduction; exocytosis; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; generation of precursor metabolites and energy; glucose homeostasis; hormone-mediated signaling; positive regulation of GTPase activity; regulation of blood pressure; response to nutrient; response to starvation

Disease: Diabetes Mellitus, Noninsulin-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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