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gld-1 recombinant protein :: Female germline-specific tumor suppressor gld-1 (gld-1) Recombinant Protein

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Catalog # MBS1427152
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $880 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $950 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,180 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,290 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,300 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,425 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,460 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,710 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,970 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,220 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,300 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,315 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,425 +4 FREE 8GB USB
gld-1 recombinant protein
Product Name

Female germline-specific tumor suppressor gld-1 (gld-1), Recombinant Protein

Full Product Name

Recombinant Caenorhabditis elegans Female germline-specific tumor suppressor gld-1 (gld-1)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-463aa, full length protein
Sequence
MPSCTTPTYG VSTQLESQSS ESPSRSSVMT PTSLDGDNSP RKRFPIIDNV PADRWPSTRR DGWSSVRAPP PARLTLSTNN RHIMSPISSA YSQTPNSLLS PAMFNPKSRS IFSPTLPATP MSYGKSSMDK SLFSPTATEP IEVEATVEYL ADLVKEKKHL TLFPHMFSNV ERLLDDEIGR VRVALFQTEF PRVELPEPAG DMISITEKIY VPKNEYPDYN FVGRILGPRG MTAKQLEQDT GCKIMVRGKG SMRDKSKESA HRGKANWEHL EDDLHVLVQC EDTENRVHIK LQAALEQVKK LLIPAPEGTD ELKRKQLMEL AIINGTYRPM KSPNPARVMT AVPLLSPTPL RSSGPVLMSP TPGSGLPSTT FGGSILSPTL TASNLLGSNV FDYSLLSPSM FDSFSSLQLA SDLTFPKYPT TTSFVNSFPG LFTSASSFAN QTNTNVSPSG ASPSASSVNN TSF
3D Structure
ModBase 3D Structure for Q17339
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Caenorhabditis elegans
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of gld-1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for gld-1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,586 Da
NCBI Official Full Name
Female germline-specific tumor suppressor gld-1
NCBI Official Symbol
gld-1  [Similar Products]
NCBI Protein Information
Female germline-specific tumor suppressor gld-1
UniProt Protein Name
Female germline-specific tumor suppressor gld-1
UniProt Synonym Protein Names
Defective in germ line development protein 1
UniProt Gene Name
gld-1  [Similar Products]
UniProt Comments for gld-1
RNA-binding protein which recognizes the 5'-UACUCAU-3' RNA consensus sequence (PubMed:24838563). Binds sequences in both the 5'coding and the 3'-UTR region of rme-2 mRNA (PubMed:11562350). Binds sequences in the 3'-UTR region of cye-1 mRNA. Binds to cyb-2.1, cyb-2.2 and cyb-3 mRNA (PubMed:19758560). Binds sequences in the 3'-UTR region of tra-2 mRNA (PubMed:24838563). Germ line-specific tumor suppressor essential for oogenesis (PubMed:7601353). Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline (PubMed:7601353, PubMed:11562350, PubMed:24838563). Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation (PubMed:11562350). By regulating cye-1 expression, prevents entry into mitosis in meiotic germline cells (PubMed:19758560, PubMed:21455289).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with gld-1 recombinant protein
Diseases associated with gld-1 recombinant protein
Organs/Tissues associated with gld-1 recombinant protein
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