NP_006842.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,919 Da
NCBI Official Full Name
glioma pathogenesis-related protein 1
NCBI Official Synonym Full Names
GLI pathogenesis related 1
NCBI Protein Information
glioma pathogenesis-related protein 1
UniProt Protein Name
Glioma pathogenesis-related protein 1
UniProt Synonym Protein Names
Protein RTVP-1
UniProt Synonym Gene Names
UniProt Entry Name
GLIP1_HUMAN
NCBI Summary for GLIPR1
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
UniProt Comments for GLIPR1
GLIPR1: a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q21.2
Cellular Component: membrane; plasma membrane
Research Articles on GLIPR1
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Pathways associated with GLIPR1 recombinant protein
Diseases associated with GLIPR1 recombinant protein
Organs/Tissues associated with GLIPR1 recombinant protein
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